Impact of Glaucoma and Visual Field Loss on Life Space



Status:Recruiting
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:10/13/2018
Start Date:October 9, 2018
End Date:September 1, 2020
Contact:Karen Searcey
Email:karensearcey@uabmc.edu
Phone:205-325-8310

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Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults

Mobility refers to a person's purposeful movement through the environment from one place to
another and can be conceptualized as a continuum from bed bound (immobility) on one extreme
to making excursions to distant locations on the other extreme. Primary open-angle glaucoma
(POAG) is a chronic, progressive optic neuropathy that can lead to gradual loss of vision in
the peripheral field and central vision. Older adults with POAG have an increased risk for
motor vehicle collisions and falls. Moreover, existing studies suggest that patients with
POAG exhibit more postural sway while standing as measured by a balance platform and also
tend to walk more slowly than those who are normally sighted and free of ocular disease.
While these disturbances likely influence mobility, there has been little research directly
assessing the impact of POAG on mobility. This study will assess the impact of POAG on life
space (one aspect of mobility) and will determine whether difficulties with life space are
associated with difficulties experienced under conditions of dim lighting.

Aim 1: To examine the extent of life space in older adults with POAG using the Life Space
Questionnaire and to examine whether life space in persons with POAG is associated with the
magnitude of visual field impairment.

Aim 2: To examine difficulties seeing under dim illumination and at night in older adults
with POAG using the Low Luminance Questionnaire and to examine whether greater difficulty in
seeing under dim illumination and at night is related to the magnitude of visual field loss.

Aim 3: To examine the relationship in older adults with POAG between visual problems seeing
under dim illumination and at night (Low Luminance Questionnaire) and their life space (Life
Space Questionnaire).

Inclusion Criteria:

- Clinical diagnosis of primary open-angle glaucoma

- Best-corrected visual acuity of 20/40 or better

- Spherical refraction within ± 5 Diopters

- Cylinder refraction within ± 3 Diopters

Exclusion Criteria:

- History of intra-ocular surgery other than uncomplicated cataract or glaucoma surgery

- Significant cognitive impairment
We found this trial at
1
site
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
Principal Investigator: Lyne Racette, PhD
Phone: 205-325-8616
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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Birmingham, AL
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