Tailored Smoking Cessation Intervention in Promoting Sexual and Gender Minority Smokers to Quit Smoking

PRIMARY OBJECTIVES:

I. To test the feasibility of two different approaches for smoking cessation (print materials
developed for smoking cessation among the mainstream population versus [vs.] an
individualized text based approach) among 60 lesbian, gay, bisexual, and transgender (LGBT)
smokers.

SECONDARY OBJECTIVES:

I. To assess the levels of helpfulness, appropriateness, and perceived difficulty of the
above mentioned cessation approaches among 60 LGBT smokers.

EXPLORATORY OBJECTIVES:

I. To test the smoking abstinence rates of two different individualized intensive cessation
approaches (mainstream vs. individually-tailored) among 60 LGBT smokers.

OUTLINE: Participants are randomized to 1 of 2 arms.

ARM I: Participants receive mainstream instructional care including brief advice on how to
quit smoking, 10-week supply of nicotine replacement therapy (NRT) in the form of nicotine
patches, and intensive print materials to promote smoking cessation.

ARM II: Participants receive tailored intensive care including brief advice on how to quit
smoking, NRT, and intensive print materials to promote smoking cessation as in Arm I.
Participants also receive individualized text based messages to promote smoking cessation for
6 months.

After completion of study, participants are followed up at 3 and 6 months.

Inclusion Criteria:

- Male or female owning a cell phone with a reachable contact number

- Self-identified as LGBT individual, regardless human immunodeficiency virus (HIV)
serologic status

- Smoked at least 100 cigarettes in lifetime

- Currently smoking at least 5 cigarettes a day, on average

- Willing to set a quit smoking date within a week of the enrollment

- English speaking

Exclusion Criteria:

- Expired carbon monoxide (CO) levels below 7 ppm

- Positive history of a medical condition that precludes use of the nicotine patch
(e.g., recent myocardial infarction, significant skin disorder, previous severe
adverse reaction to nicotine patch, pregnant or breast feeding, assessed with our
standard protocol for determining NRT eligibility)

- Current use of NRT or other smoking cessation medications (e.g., varenicline or
bupropion)

- Pregnant or nursing

- Enrolled in another smoking cessation program

- Partner enrolled on current study