Pain Outcomes Following Intralesional Corticosteroid Injections



Status:Recruiting
Conditions:Acne, Acne, Psoriasis, Skin and Soft Tissue Infections, Orthopedic, Dermatology, Dermatology, Dermatology, Dermatology, Hair Loss
Therapuetic Areas:Dermatology / Plastic Surgery, Orthopedics / Podiatry
Healthy:No
Age Range:12 - Any
Updated:2/2/2019
Start Date:October 1, 2018
End Date:September 2019
Contact:Brian C Drolet, MD
Email:brian.c.drolet@vanderbilt.edu
Phone:(615) 322-7311

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The Use of Local Anesthetic in Intralesional Corticosteroid Injections; A Randomized, Double Blind Controlled Trial

Corticosteroid therapy, including intralesional and topical applications, has many
indications within the fields of Dermatology, Plastic Surgery, and Orthopedics. However,
these injections can be quite painful, which leads many patients to discontinue treatment.

Often, the injection involves a mixture of local anesthetic and corticosteroids despite a
lack of evidence that the use of lidocaine improves pain. Due to the acidic pH, the lidocaine
component of the injection can actually cause a significant burning sensation during the
procedure. Lidocaine does not have anti-inflammatory properties and does not treat the
underlying pathology. By including another medication, lidocaine also adds cost and risk to
the procedure.

The purpose of this study is to see if removing lidocaine from intralesional injections
decreases the pain of injection.


Inclusion Criteria:

- >12 years old presenting with an indication for intralesional steroid injection

Exclusion Criteria:

- Unconsentable

- Not a candidate for corticosteroid injection

- Contraindication to lidocaine
We found this trial at
1
site
1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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