Mupirocin-Iodophor ICU Decolonization Swap Out Trial



Status:Recruiting
Conditions:Infectious Disease
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:Any
Updated:8/8/2018
Start Date:May 1, 2017
End Date:December 2023
Contact:Katie Haffenreffer
Email:Katie_Haffenreffer@hphc.org
Phone:617-867-4807

Use our guide to learn which trials are right for you!

Cluster-randomized Non-inferiority Trial Comparing Mupirocin vs Iodophor for Nasal Decolonization of ICU Patients to Assess Impact on S. Aureus Clinical Cultures and All-cause Bloodstream Infection During Routine Chlorhexidine Bathing

The Swap Out Trial is a cluster randomized controlled trial of HCA hospitals, evaluating the
non-inferiority of two decolonization regimens:

Arm 1 Routine Care: ICU nasal decolonization with mupirocin twice daily for 5 days in the
context of chlorhexidine for daily bathing; Arm 2 Intervention: ICU nasal decolonization with
iodophor twice daily for 5 days in the context of chlorhexidine for daily bathing Note: that
enrolled "subjects" represents 137 individual HCA Hospitals (representing ~235 ICUs) that
have been randomized.


Inclusion Criteria:

- Inclusion criteria includes all U.S. HCA hospitals with an adult ICU;

- Note: Unit of randomization is the hospital, but the participants are hospital adult
ICUs

- All patients within adult ICUs are included, including rare patients <18 years and
>=12 years.

Exclusion Criteria:

- Exclusion criteria includes ICUs with an average length of stay of less than 2 days;

- HCA hospitals that are not able to transfer or merge data into the centralized data
warehouse for the baseline and intervention periods of the study are also excluded.
We found this trial at
137
sites
Fort Worth, Texas 76104
?
mi
from
Fort Worth, TX
Click here to add this to my saved trials
7777 Forest Ln # C840
Dallas, Texas 75230
(972) 566-7000
Medical City Dallas Hospital If you have concerns for your health, that of a family...
?
mi
from
Dallas, TX
Click here to add this to my saved trials
1719 East 19th Avenue
Denver, Colorado 80218
(303) 839-6000
Presbyterian - St. Luke's Medical Center Presbyterian/St. Luke's Medical Center and the Rocky Mountain Hospital...
?
mi
from
Denver, CO
Click here to add this to my saved trials
211 4th Street
Alexandria, Louisiana 71301
?
mi
from
Alexandria, LA
Click here to add this to my saved trials
Arlington, Texas 76015
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Atlantis, Florida 33462
?
mi
from
Atlantis, FL
Click here to add this to my saved trials
Augusta, Georgia 30909
?
mi
from
Augusta, GA
Click here to add this to my saved trials
1501 S Potomac St
Aurora, Colorado 80012
(303) 695-2600
Medical Center of Aurora At The Medical Center of Aurora and Centennial Medical Plaza patients...
?
mi
from
Aurora, CO
Click here to add this to my saved trials
Austin, Texas 78745
?
mi
from
Austin, TX
Click here to add this to my saved trials
Austin, Texas 78758
?
mi
from
Austin, TX
Click here to add this to my saved trials
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
Belton, Missouri 64012
?
mi
from
Belton, MO
Click here to add this to my saved trials
Blacksburg, Virginia 24060
?
mi
from
Blacksburg, VA
Click here to add this to my saved trials
Bountiful, Utah 84010
?
mi
from
Bountiful, UT
Click here to add this to my saved trials
Bowling Green, Kentucky 42104
?
mi
from
Bowling Green, KY
Click here to add this to my saved trials
Bradenton, Florida 34209
?
mi
from
Bradenton, FL
Click here to add this to my saved trials
Brandon, Florida 33511
?
mi
from
Brandon, FL
Click here to add this to my saved trials
Brooksville, Florida 34613
?
mi
from
Brooksville, FL
Click here to add this to my saved trials
Brownsville, Texas 78526
?
mi
from
Brownsville, TX
Click here to add this to my saved trials
Caldwell, Idaho 83605
?
mi
from
Caldwell, ID
Click here to add this to my saved trials
Cartersville, Georgia 30120
?
mi
from
Cartersville, GA
Click here to add this to my saved trials
Charleston, South Carolina 29406
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Chattanooga, Tennessee 37404
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
Chattanooga, Tennessee 37412
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
Conroe, Texas 77304
?
mi
from
Conroe, TX
Click here to add this to my saved trials
Corpus Christi, Texas 78411
?
mi
from
Corpus Christi, TX
Click here to add this to my saved trials
?
mi
from
Corpus Christi, TX
Click here to add this to my saved trials
Covington, Louisiana 70433
?
mi
from
Covington, LA
Click here to add this to my saved trials
Denton, Texas 76210
?
mi
from
Denton, TX
Click here to add this to my saved trials
Denver, Colorado 80110
?
mi
from
Denver, CO
Click here to add this to my saved trials
Denver, Colorado 80124
?
mi
from
Denver, CO
Click here to add this to my saved trials
4567 E 9th Ave
Denver, Colorado 80220
(303) 320-2121
Rose Medical Center Well known as a Denver institution and a 9th Avenue landmark for...
?
mi
from
Denver, CO
Click here to add this to my saved trials
Derry, New Hampshire 03038
?
mi
from
Derry, NH
Click here to add this to my saved trials
Dublin, Georgia 31021
?
mi
from
Dublin, GA
Click here to add this to my saved trials
El Paso, Texas 79902
?
mi
from
El Paso, TX
Click here to add this to my saved trials
El Paso, Texas 79925
?
mi
from
El Paso, TX
Click here to add this to my saved trials
Englewood, Florida 34223
?
mi
from
Englewood, FL
Click here to add this to my saved trials
Fort Pierce, Florida 34950
?
mi
from
Fort Pierce, FL
Click here to add this to my saved trials
Fort Walton Beach, Florida 32547
?
mi
from
Fort Walton Beach, FL
Click here to add this to my saved trials
Fredericksburg, Pennsylvania 22408
?
mi
from
Fredericksburg, PA
Click here to add this to my saved trials
Gainesville, Florida 32605
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
Gulfport, Mississippi 39503
?
mi
from
Gulfport, MS
Click here to add this to my saved trials
Hendersonville, Tennessee 37075
?
mi
from
Hendersonville, TN
Click here to add this to my saved trials
Hermitage, Tennessee 37076
?
mi
from
Hermitage, TN
Click here to add this to my saved trials
Hopewell, Virginia 23860
?
mi
from
Hopewell, VA
Click here to add this to my saved trials
?
mi
from
Houston, TX
Click here to add this to my saved trials
Houston, Texas 77082
?
mi
from
Houston, TX
Click here to add this to my saved trials
14000 Fivay Road
Hudson, Florida 34667
?
mi
from
Hudson, FL
Click here to add this to my saved trials
Idaho Falls, Idaho 83404
?
mi
from
Idaho Falls, ID
Click here to add this to my saved trials
Independence, Missouri 64057
?
mi
from
Independence, MO
Click here to add this to my saved trials
Irving, Texas 75039
?
mi
from
Irving, TX
Click here to add this to my saved trials
Jacksonville, Florida 32216
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
2316 E Meyer Blvd
Kansas City, Missouri 64132
(816) 276-4000
Research Medical Center Research Medical Center offers hospital and health clinic services across three Kansas...
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Kingwood, Texas
?
mi
from
Kingwood, TX
Click here to add this to my saved trials
Kissimmee, Florida 34741
?
mi
from
Kissimmee, FL
Click here to add this to my saved trials
Kissimmee, Florida 34758
?
mi
from
Kissimmee, FL
Click here to add this to my saved trials
Lake City, Florida 32055
?
mi
from
Lake City, FL
Click here to add this to my saved trials
Largo, Florida 33770
?
mi
from
Largo, FL
Click here to add this to my saved trials
Las Vegas, Nevada 89109
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Las Vegas, Nevada 89128
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Las Vegas, Nevada 89148
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Lee's Summit, Missouri 64063
?
mi
from
Lee's Summit, MO
Click here to add this to my saved trials
Lewisville, Texas 75057
?
mi
from
Lewisville, TX
Click here to add this to my saved trials
Low Moor, Virginia 24457
?
mi
from
Low Moor, VA
Click here to add this to my saved trials
13001 Southern Boulevard
Loxahatchee Groves, Florida 33470
?
mi
from
Loxahatchee Groves, FL
Click here to add this to my saved trials
Macon, Georgia 31217
?
mi
from
Macon, GA
Click here to add this to my saved trials
?
mi
from
Macon, GA
Click here to add this to my saved trials
Margate, Florida 33063
?
mi
from
Margate, FL
Click here to add this to my saved trials
McAllen, Texas 78503
?
mi
from
McAllen, TX
Click here to add this to my saved trials
McKinney, Texas 75069
?
mi
from
McKinney, TX
Click here to add this to my saved trials
Miami, Florida 33133
?
mi
from
Miami, FL
Click here to add this to my saved trials
Miami, Florida 33175
?
mi
from
Miami, FL
Click here to add this to my saved trials
Myrtle Beach, South Carolina 29572
?
mi
from
Myrtle Beach, SC
Click here to add this to my saved trials
Nashville, Tennessee 37167
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Nashville, Tennessee 37203
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Nashville, Tennessee 37207
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Nashville, Tennessee 37211
?
mi
from
Nashville, TN
Click here to add this to my saved trials
New Orleans, Louisiana 70112
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
Niceville, Florida 32578
?
mi
from
Niceville, FL
Click here to add this to my saved trials
North Richland Hills, Texas 76180
?
mi
from
North Richland Hills, TX
Click here to add this to my saved trials
Ocala, Florida 34480
?
mi
from
Ocala, FL
Click here to add this to my saved trials
Ocala, Florida 34474
?
mi
from
Ocala, FL
Click here to add this to my saved trials
5475 South 500 East
Ogden, Utah 84405
?
mi
from
Ogden, UT
Click here to add this to my saved trials
Okeechobee, Florida 34972
?
mi
from
Okeechobee, FL
Click here to add this to my saved trials
Orange Park, Florida 32073
?
mi
from
Orange Park, FL
Click here to add this to my saved trials
750 West 800 North
Orem, Utah 84057
?
mi
from
Orem, UT
Click here to add this to my saved trials
5721 W 119th St
Overland Park, Kansas 66209
(913) 498-6000
Menorah Medical Center Menorah Medical Center (MMC), a full-service, acute care hospital located on the...
?
mi
from
Overland Park, KS
Click here to add this to my saved trials
Overland Park, Kansas 66215
?
mi
from
Overland Park, KS
Click here to add this to my saved trials
Panama City, Florida 32405
?
mi
from
Panama City, FL
Click here to add this to my saved trials
Pasadena, Texas 77504
?
mi
from
Pasadena, TX
Click here to add this to my saved trials
Payson, Utah 84651
?
mi
from
Payson, UT
Click here to add this to my saved trials
Pensacola, Florida 32514
?
mi
from
Pensacola, FL
Click here to add this to my saved trials
Plano, Texas 75075
?
mi
from
Plano, TX
Click here to add this to my saved trials
Plantation, Florida 33317
?
mi
from
Plantation, FL
Click here to add this to my saved trials
Plantation, Florida 33324
?
mi
from
Plantation, FL
Click here to add this to my saved trials
Port Charlotte, Florida 33952
?
mi
from
Port Charlotte, FL
Click here to add this to my saved trials
Port Saint Lucie, Florida 34952
?
mi
from
Port Saint Lucie, FL
Click here to add this to my saved trials
Portsmouth, New Hampshire 03801
?
mi
from
Portsmouth, NH
Click here to add this to my saved trials
Pulaski, Virginia 24301
?
mi
from
Pulaski, VA
Click here to add this to my saved trials
Reston, Virginia 20190
?
mi
from
Reston, VA
Click here to add this to my saved trials
?
mi
from
Richmond, VA
Click here to add this to my saved trials