Internet-based CBT After Stroke Pilot



Status:Recruiting
Conditions:Depression, Neurology
Therapuetic Areas:Neurology, Psychiatry / Psychology
Healthy:No
Age Range:18 - 99
Updated:11/23/2018
Start Date:June 11, 2018
End Date:April 1, 2020
Contact:Nichole Gallatti
Email:nichole.gallatti@uphs.upenn.edu
Phone:215-349-8651

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Internet-based Cognitive Behavioral Therapy to Reduce Depressive Symptoms After Stroke Pilot/Feasibility Study

Mood disorders occur in 25-30% of stroke patients and are associated with lower quality of
life, higher mortality, increased healthcare utilization, and higher costs. Cognitive
behavioral therapy (CBT) interventions have been shown to both treat and prevent post-stroke
mood disorders, thus having the ability to improve quality of life and reduce costs. This
study aims to test the feasibility of internet-based CBT combined with a telephone/email
based coaching service after stroke.


Inclusion Criteria:

- Age ≥18 years of age

- Acute ischemic stroke within the past 3 months

- Regular access to the internet, sufficient to allow a minimum of interactions with the
internet daily, either through a personal smartphone or web-based internet browser.

- Subject is willing and able to participate in internet-based cognitive behavioral
therapy

- Can participate in the program in English

- Willingness and ability to sign informed consent by the patient

- Symptoms of mild to moderately depressed mood, defined as a score of 5-19 on the
Patient Health Questionnaire-9 at the time of study enrollment.

Exclusion Criteria:

- Severely depressed patients, defined by a score of 20+ on the Patient Health
Questionnare-9 are excluded

- Patients with an active bipolar disorder diagnosis are excluded

- Patients with personality disorder diagnoses are excluded

- Patients with active suicidality or past suicide attempts are excluded

- History of schizophrenia or schizoaffective disorder

- Active participation in face-to-face psychotherapy prior to stroke

- Patients with a history of dementia are excluded

- Patients with aphasia, defined as a score of 1 or greater on NIH Stroke Scale Item 9
are excluded.

- Patients without regular internet access through a computer, tablet or smartphone are
excluded.

- Subjects requiring long-term inpatient nursing care are excluded. For patients
enrolled as inpatients, individuals being discharged to both home and acute rehab are
eligible. Individuals being discharged to a skilled nursing facility or hospice are
excluded.

- Expected life expectancy less than 6 months or other inability to comply with study
follow-up.

- Pregnant women and prisoners are excluded
We found this trial at
1
site
3451 Walnut St
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Principal Investigator: Michael T Mullen, MD
Phone: 215-349-8651
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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