Specimen Repository for HIV Immunopathogenesis

The goal is to build a large specimen repository for collaborating scientists to run studies
of immunity and HIV-1.

Inclusion Criteria:

1. HIV positive (acutely infected, viremic and elite controllers)

2. Signed Informed Consent Form

3. Age at least 18 years old

4. Immune controllers, two types: "Elite suppressors" (HIV-positive with any three
consecutive plasma HIV-1 RNA PCR undetectable while off treatment) or "viremic
suppressors" (HIV-positive with any three consecutive HIV-1 RNA PCR <3000 while off
treatment).

5. Acutely infected subjects:

Persons identified to have a negative HIV antibody response (ELISA) but positive detection
of HIV-1 in the blood (RT-PCR) or individuals who have evidence of a recent (past 30 days)
HIV negative result along with a current HIV positive result.

Exclusion Criteria:

1. Uncontrolled bleeding diathesis.

2. Pregnant.

3. Inability to provide informed consent.