Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)
| Status: | Recruiting |
|---|---|
| Conditions: | Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 21 - 55 |
| Updated: | 10/11/2018 |
| Start Date: | September 1, 2018 |
| End Date: | June 2022 |
| Contact: | Frances Wagner, RN |
| Email: | fpwagn2@uky.edu |
| Phone: | 859-257-5388 |
A Novel Drug Combination for Alcohol-Use Disorders: A Human Laboratory Study
This study will evaluate the behavioral effects of alcohol during maintenance on placebo,
duloxetine, methylphenidate and duloxetine combined with methylphenidate using sophisticated
human laboratory methods.
duloxetine, methylphenidate and duloxetine combined with methylphenidate using sophisticated
human laboratory methods.
Inclusion Criteria:
- able to speak/read English
- not seeking treatment at the time of the study
- one binge drinking episode (5+/4+ standard alcoholic drinks per drinking session for
men and women, respectively) in the past 30 days
- recent alcohol use verified by ethyl glucuronide positive urine, as well as
fulfillment of DSM-5 diagnostic criteria for alcohol use disorder
- ECG within normal limits
- otherwise healthy
- body mass index of 19-35
- females using an effective form of birth control and not pregnant or breast feeding
- judged by the medical staff to be psychiatrically and physically healthy
- able to abstain from alcohol for 12 hours prior to session
- no contraindications/allergies to duloxetine or methylphenidate
We found this trial at
1
site
Lexington, Kentucky
859) 257-9000
Principal Investigator: Craig Rush, PhD
Phone: 859-257-5388
University of Kentucky The University of Kentucky is a public, land grant university dedicated to...
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