CO2 Laser Phototherapy for Management of Mature Burn Scars

Laser phototherapy has gained growing acceptance and popularity for management of burn scars.
The most commonly used laser is the Carbon Dioxide (CO2) Laser. At this institution, the
investigator has used CO2 for management of Burn Scars since 2012. While the existing
literature and the investigator's anecdotal experience thus far has been positive overall,
there is no conclusive evidence to support that CO2 does indeed improve the quality of mature
burn scars

The primary objective of this study is to evaluate mature burn scars before and after
treatment with CO2 for patients age 3-21 while comparing the treated areas to an untreated
control area in the same patient.

Inclusion Criteria:

- Age 3 to 21

- Patients with mature burn scars that are at least two years old from burn injury and
that have not previously undergone CO2 laser therapy for scar revision.

- Scars in all body areas with the exception of face, genitals or hands will be
considered eligible for the study

- Entry into this study is open to pediatric patients of both genders.

- Entry into this study is open to pediatric patients of all ethnic backgrounds.

- Entry into this study is open to females of childbearing potential with a negative
urine or serum pregnancy test

Exclusion Criteria:

- Patients with scars less than 2 years old

- Patients with contraindications to laser treatment (i.e.: active acne infections/
treatment with isotretinoin, active Zoster infection)

- Patients receiving other forms of scar revision therapy such as other laser types,
steroid injections, or surgical excisions.