COREG MR Versus TOPROL-XL On The Lipid Profile Of Normolipidemic Or Mildly Dyslipidemic Patients With Hypertension



Status:Completed
Conditions:High Blood Pressure (Hypertension)
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 80
Updated:6/27/2018
Start Date:January 5, 2006
End Date:December 28, 2007

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Trial Summary
Trial Overview
Inclusion Criteria

A Randomized, Double-Blind, Multi-Center Study Comparing the Effects of Carvedilol Phosphate Modified Release Formulation (COREG- MR) With Metoprolol Succinate (TOPROL XL) on the Lipid Profile in Normolipidemic, or Mildly Dyslipidemic Hypertensive Patients

This study was designed to determine whether treatment with COREG MR is more effective at
maintaining a better lipid profile than treatment with TOPROL-XL for hypertension.


Inclusion Criteria:

- Documented history of hypertension

- Triglycerides of 120-400 mg/mL

- LDLc levels not requiring lipid lowering medication.

Exclusion Criteria:

- Has known contraindication to alpha- or beta-blocker therapy.

- Has taken any non-ocular beta-blockers within three months before screening.

- Has Type I or II diabetes.

- Taking lipid lowering medications.
We found this trial at
88
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GSK Investigational Site
Manassas, Virginia 20109
2255
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Manassas, VA
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Albuquerque, New Mexico 87109
654
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Albuquerque, NM
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Altamonte Springs, Florida 32714
2179
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Altamonte Springs, FL
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Atlanta, Georgia 30341
1922
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Atlanta, GA
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Auburn, Maine 04210
2615
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Auburn, ME
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Aurora, Illinois 60504
1698
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Avon, Connecticut 06001
2489
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Avon, CT
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Birmingham, Alabama 35249
1777
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Birmingham, AL
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Bossier City, Louisiana 71111
1403
mi
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Bossier City, LA
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Brick, New Jersey 08723
2429
mi
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Brick, NJ
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Bristol, Tennessee 37620
2015
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Bristol, TN
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Brooklyn Center, Minnesota 55430
?
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Brooklyn Center, MN
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Burke, Virginia 22015
2268
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Burke, VA
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Calgary, Alberta
1189
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Calgary,
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Carmichael, California 95608
364
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Chandler, Arizona 85224
356
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Charlotte, North Carolina 28203
2100
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Chicago, Illinois 60611
1730
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Cincinnati, Ohio 45229
1880
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Clearwater, Florida 33759
2122
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Cleveland, Ohio 44195
2036
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Columbia, South Carolina 29203
2102
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Corpus Christi, Texas 78405
1291
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Corpus Christi, TX
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Detroit, Michigan 48202
1965
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Detroit, MI
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East Syracuse, New York 13057
2322
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East Syracuse, NY
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Elizabeth, New Jersey 07201
2422
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Elizabeth, NJ
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Endwell, New York 13760
2325
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Erie, Pennsylvania 16507
2116
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Evansville, Indiana 47714
1716
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Evansville, IN
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Fayetteville, Arkansas 72703
1354
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Fishkill, New York 12524
2435
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Fishkill, NY
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Fort Lauderdale, Florida 33308
2315
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Fort Lauderdale, FL
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Galax, Virginia 24333
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Gillespie, Illinois 62033
1595
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Greer, South Carolina 29651
2027
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Hartsville, South Carolina 29550
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Healdsburg, California 95448
413
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Henderson, Nevada 89052
213
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Indianapolis, Indiana 46202
1793
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Irvine, California 92697
31
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Jacksonville, Florida 32207
2131
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Kettering, Ohio 45429
1899
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Kingsport, Tennessee 37660
1994
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La Jolla, California 92093
93
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Las Vegas, Nevada 89102
214
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Lewisburg, West Virginia 24901
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Little Rock, Arkansas 72205
1459
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Los Angeles, California 90025
24
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Marietta, Georgia 30060
1908
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Mesa, Arizona 85206
365
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Mission Viejo, California 92691
37
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Montgomery, Alabama 36109
1831
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Natick, Massachusetts 01760
2563
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New York, New York 10032
2435
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Newport News, Virginia 23606
2322
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Oklahoma City, Oklahoma 73112
1161
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Olive Branch, Mississippi 38654
1600
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Omaha, Nebraska 68131
1299
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Pembroke Pines, Florida 33028
2306
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Phoenix, Arizona 85012
343
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Poway, California 92064
95
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Raleigh, North Carolina 27614
2217
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Richmond, Virginia 23298
2269
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Roswell, Georgia 30076
1919
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Sacramento, California 95815
365
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Saint Louis, Missouri 63110
1570
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Salt Lake City, Utah 84132
573
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San Antonio, Texas 78258
1184
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San Diego, California 92111
99
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Simpsonville, South Carolina 29681
2028
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Spring Valley, California 91978
324
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Springfield, Missouri 65807
1398
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Springfield, Virginia 22151
2273
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Statesville, North Carolina 28625
2093
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Stockton, California 95207
328
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Taunton, Massachusetts 02780
2578
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Torrance, California 90502
22
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Tucson, Arizona 85724
427
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Vernon Hills, Illinois 60061
1716
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Virginia Beach, Virginia 23456
2352
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Vista, California 92083
74
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Walla Walla, Washington 99362
828
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Warminster, Pennsylvania 18974
2377
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West Chester, Pennsylvania 19380
2352
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West Yarmouth, Massachusetts 02673
2623
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Wichita, Kansas 67207
1186
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Wilmington, North Carolina 28405
2282
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Winston-Salem, North Carolina 27103
2122
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