Proton Boost in Prostate Cancer



Status:Enrolling by invitation
Conditions:Prostate Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:6/22/2018
Start Date:April 16, 2018
End Date:April 2033

Use our guide to learn which trials are right for you!

Assessing the Effectiveness of Photon Therapy With a Proton Therapy Boost in the Treatment of Prostate Cancer as Compared to Photon Therapy Alone

This study uses photon radiation with a proton boost to treat prostate cancer. The purpose of
this study is to determine if proton therapy as a boost following photon intensity modulated
radiation therapy (IMRT) produces decreased toxicity as compared to conventional photon IMRT
alone in the treatment of prostate cancer. Our secondary objective is to determine the
effectiveness of this treatment regimen. Effectiveness will be determined by length of time
to progression or recurrence of disease and overall survival. Patients on this study will be
treated with a course of photon radiation therapy followed by a boost course of proton
radiation.


Inclusion Criteria:

- ≥18 years of age

- Diagnosis of low risk prostate cancer (T1c-T2a, Gleason 6, Prostate Specific Antigen
(PSA) <10) -OR-

- Diagnosis of intermediate risk prostate cancer (T1c-T2c, Gleason 7 and/or PSA 10- 20)

- Life expectancy >10 yrs

- Physically and mentally capable of signing the consent form of their own volition

Exclusion Criteria:

- < 18 years of age

- Diagnosis of high risk prostate cancer (T3 or higher, Gleason >7 and/or PSA >20)

- Current or historical use of androgen deprivation therapy

- Nodal positivity

- Previous cancer excluding non-melanoma skin cancer

- History of prostatectomy

- History of brachytherapy for prostate cancer

- Life expectancy <10 yrs

- Physically or mentally incapable of signing the consent form of their own volition
We found this trial at
1
site
2600 Clifton Ave
Cincinnati, Ohio 45267
(513) 556-6000
University of Cincinnati The University of Cincinnati offers students a balance of educational excellence and...
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials