A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis



Status:Recruiting
Conditions:Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - Any
Updated:3/21/2019
Start Date:June 13, 2018
End Date:August 2020
Contact:UCB Cares
Email:UCBCares@ucb.com
Phone:+1844599

Use our guide to learn which trials are right for you!

A Multicenter, Randomized, Double-Blind, Secukinumab-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

This is a study to compare the efficacy of bimekizumab versus secukinumab in subjects with
moderate to severe chronic plaque psoriasis (PSO).


Inclusion Criteria:

- Male or female at least 18 years of age

- Subject must have had chronic plaque psoriasis (PSO) for at least 6 months prior to
the Screening visit

- Subject must have Psoriasis Area Severity Index (PASI) >=12 and body surface area
(BSA) affected by PSO >=10% and Investigator's Global Assessment (IGA) score >=3 on a
5 point scale

- Subject must be a candidate for systemic PSO therapy and/or phototherapy

- Subject must be considered, in the opinion of the Investigator, to be a suitable
candidate for treatment with secukinumab per regional labeling and has no
contraindications to receive secukinumab as per the local label

- Female subject of child bearing potential must be willing to use highly effective
method of contraception

Exclusion Criteria:

- Subject has an active infection (except common cold), a serious infection, or a
history of opportunistic, recurrent or chronic infections

- Subject has concurrent acute or chronic viral hepatitis B or C or human
immunodeficiency virus (HIV) infection

- Subject has known tuberculosis (TB) infection, is at high risk of acquiring TB
infection, or has current or history of nontuberculous mycobacterium (NTMB) infection

- Subject has any other condition, including medical or psychiatric, which, in the
Investigator's judgment, would make the subject unsuitable for inclusion in the study

- Presence of active suicidal ideation or severe depression

- Subject has any active malignancy or history of malignancy within 5 years prior to the
Screening Visit EXCEPT treated and considered cured cutaneous squamous or basal cell
carcinoma, or in situ cervical cancer
We found this trial at
24
sites
Saint Louis, Missouri
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Bexley, Ohio
?
mi
from
Bexley, OH
Click here to add this to my saved trials
Carlton,
?
mi
from
Carlton,
Click here to add this to my saved trials
Coral Gables, Florida 33134
?
mi
from
Coral Gables, FL
Click here to add this to my saved trials
Dallas, Texas
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Danbury, Connecticut 06810
?
mi
from
Danbury, CT
Click here to add this to my saved trials
Forest Hills, New York 11375
?
mi
from
Forest Hills, NY
Click here to add this to my saved trials
High Point, North Carolina
?
mi
from
High Point, NC
Click here to add this to my saved trials
Houston, Texas
?
mi
from
Houston, TX
Click here to add this to my saved trials
New Orleans, Louisiana 70115
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
Ocala, Florida 34471
?
mi
from
Ocala, FL
Click here to add this to my saved trials
Ormond Beach, Florida
?
mi
from
Ormond Beach, FL
Click here to add this to my saved trials
Pembroke Pines, Florida 33028
?
mi
from
Pembroke Pines, FL
Click here to add this to my saved trials
Pflugerville, Texas 78660
?
mi
from
Pflugerville, TX
Click here to add this to my saved trials
Portland, Oregon
?
mi
from
Portland, OR
Click here to add this to my saved trials
Portsmouth, New Hampshire
?
mi
from
Portsmouth, NH
Click here to add this to my saved trials
Sandy Springs, Georgia 30329
?
mi
from
Sandy Springs, GA
Click here to add this to my saved trials
Santa Ana, California 92701
?
mi
from
Santa Ana, CA
Click here to add this to my saved trials
Skokie, Illinois 60077
?
mi
from
Skokie, IL
Click here to add this to my saved trials
Tampa, Florida 33624
?
mi
from
Tampa, FL
Click here to add this to my saved trials
West des Moines, Iowa
?
mi
from
West des Moines, IA
Click here to add this to my saved trials
West Dundee, Illinois
?
mi
from
West Dundee, IL
Click here to add this to my saved trials
West Palm Beach, Florida
?
mi
from
West Palm Beach, FL
Click here to add this to my saved trials
Wilmington, North Carolina
?
mi
from
Wilmington, NC
Click here to add this to my saved trials