Thromboelastogram in Postdelivery Preeclamptic Patients
| Status: | Recruiting |
|---|---|
| Conditions: | Women's Studies, Hematology |
| Therapuetic Areas: | Hematology, Reproductive |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/3/2019 |
| Start Date: | May 22, 2018 |
| End Date: | December 31, 2019 |
| Contact: | Efrain Riveros Perez, MD |
| Email: | eriverosperez@augusta.edu |
| Phone: | 706-721-7361 |
Effect of Age on Reference Values for Thromboelastography in Pregnant Women With Pre-eclampsia
There are no studies evaluating the effect of aging on hemostasis of preeclamptic patients.
Additionally, although there are some studies that establish normal reference values for TEG
profiles in healthy term pregnant patients, conflicting results have been found in
preeclampsia. Reference values are important to establish baseline parameters in cases of
pre-eclampsia complicated by postpartum hemorrhage. The investigators will evaluate reference
values for TEG in postdelivery preeclamptic patients and the difference between vaginal
delivery and cesarean section.
Additionally, although there are some studies that establish normal reference values for TEG
profiles in healthy term pregnant patients, conflicting results have been found in
preeclampsia. Reference values are important to establish baseline parameters in cases of
pre-eclampsia complicated by postpartum hemorrhage. The investigators will evaluate reference
values for TEG in postdelivery preeclamptic patients and the difference between vaginal
delivery and cesarean section.
After approval by the Institutional Review Board and informed consent from participants, the
investigators are obtaining blood samples for TEG processing, from pregnant patients admitted
to the maternity unit of Augusta University Medical Center. Patients are being classified in
2 groups: term pregnant patients with diagnosis of pre-eclampsia who undergo cesarean section
and those having spontaneous vaginal delivery. Each group will be divided into subgroups
according to maternal age: 18-25 years, 26-35 years, >36 years. Pre-eclampsia is defined and
classified according to the definitions of the American College of Obstetricians and
Gynecologists published in 2013.
investigators are obtaining blood samples for TEG processing, from pregnant patients admitted
to the maternity unit of Augusta University Medical Center. Patients are being classified in
2 groups: term pregnant patients with diagnosis of pre-eclampsia who undergo cesarean section
and those having spontaneous vaginal delivery. Each group will be divided into subgroups
according to maternal age: 18-25 years, 26-35 years, >36 years. Pre-eclampsia is defined and
classified according to the definitions of the American College of Obstetricians and
Gynecologists published in 2013.
Inclusion Criteria:
- Age > 18 years Mental competence Gestational age > 37-week Informed consent Diagnosis
of preeclampsia (with or without features of severity)
Exclusion Criteria:
Gestational age < 37-week Known bleeding or thrombotic diathesis Use of aspirin or
unfractionated or low-molecular weight heparin within the last 48 hours BMI > 35 Maternal
comorbid conditions other than preeclampsia
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