Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism



Status:Recruiting
Conditions:Neurology, Psychiatric, Autism
Therapuetic Areas:Neurology, Psychiatry / Psychology
Healthy:No
Age Range:2 - 6
Updated:6/3/2018
Start Date:June 22, 2012
End Date:March 31, 2019
Contact:Nathan A Call, PhD
Email:Nathan.Call@choa.org
Phone:(404)419-5039

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The purpose of this study is to compare how children with autism, typically developing
children, and children with other developmental delays value social attention and toys. The
first part of the study seeks to determine whether breakpoints when responding on progressive
ratio (PR) schedules can be used to determine the value of leisure items and attention. By
comparing the breakpoints obtained for leisure items and attention, the researchers will
determine the differential valuation of leisure items and attention. It is anticipated that
the manner in which individuals with an autism spectrum disorder (ASD) diagnosis and those
who do not will differ with respect to the degree to which they value these two types of
stimuli. The second part of the study seeks to determine whether an intervention in which
social attention is paired with primary reinforcers impacts responding during the PR
assessment, in children with ASD.

The three core features of autism spectrum disorder (ASD) are impairments in social
interaction, restricted range of interest, and stereotyped/repetitive behavior. However,
autism is a heterogeneous disorder, and individuals with a diagnosis vary widely in specific
presentation. For example, despite an overall impairment in social behavior, some individuals
with an autism diagnosis still frequently initiate social interactions with others. In
contrast, others may engage in problem behaviors maintained by escape or avoidance of social
interactions.

A progressive ratio (PR) assessment is one method for directly quantifying the degree to
which an individual values a particular stimulus or event. Within a PR assessment,
reinforcement occurs under schedule requirements that increase following each set of
responses within a single session until responding ceases. The highest schedule requirement
completed (i.e., breakpoint) can then be used as a measure of how much an individual is
willing to respond for a given stimulus.

The study will include about 65 children, 25 children with ASD and 15 typically developing
children, and 25 children with developmental disabilities other than ASD. Children with
autism, typically developing children, and children with non-ASD developmental delays other
than ASD will be compared in terms of how they value social attention and toys. The child
participants will be asked to do an action, such as pressing a button, to receive either an
item or attention. At first, the participants will only be required to do the action once,
but after the first time the children will be required do more and more before they can get
the item or attention. Eventually, most children stop responding for the preferred item or
attention. The study will consider the child as done working when they go for one minute
without performing the action. Sessions will end after 30 minutes if the child keeps working
without stopping. This study will examine how many times the child will respond for items and
attention. 15 of the children with ASD will be asked to come back for an additional
appointment one week after they complete the assessment of how they value attention and toys.
The PR assessment will be repeated see if the children respond the same way at different
times.

The second part of the study will include 10 children diagnosed with ASD ranging in age from
two to six. All of the procedures described in part one of the study will be included. The PR
assessment will be completed prior to intervention and again after intervention. All
appointments will be conducted over a maximum of 4 weeks. The intervention will be based on
the principals of respondent conditioning; social interaction will be paired with the
delivery of other reinforcers, such as edible items, to increase the value of social
interaction. Sessions will be conducted 5 days per week and will be up to two hours long.
Following the intervention, the participant will repeat the PR assessment in order to assess
whether the intervention increased the value of social interaction.

Inclusion Criteria for Autism Spectrum Disorder (ASD) Group:

- Between the ages of 3 and 6.

- Presence of an autism diagnosis as determined by The Autism Diagnostic Observation
Schedule (ADOS).

- Adaptive functioning typical of autism as determined by the Vineland Adaptive Behavior
Scales (VABS-II; survey interview form).

- Completion of the Social Responsiveness Scale (SRS) to assess social impairment.

- Completion of the Early Social Communication Scales to assess non-verbal
communication.

Inclusion Criteria for Typically Developing Group:

- Between the ages of 3 and 6.

- Current developmental level determined to be not developmentally delayed per The
Mullen Scales of Early Learning (MSEL) or Differential Ability Scale (DAS; depending
on participant age).

Inclusion Criteria for Other Developmental Delays Group:

- Between the ages of 3 and 6.

- Current developmental level determined to be developmentally delayed per The Mullen
Scales of Early Learning (MSEL) or Differential Ability Scale (DAS; depending on
participant age).

Exclusion Criteria for all groups:

- Caregiver does not give permission for protective procedures and emergency protocols
to be used if the child participant exhibits problem behaviors during a study visit.

- Children who are not able to master the training trial within 10 sessions will not
participate in the study.
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Atlanta, Georgia 30329
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