Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch)



Status:Recruiting
Conditions:Allergy, Psoriasis, Dermatology, Dermatology, Dermatology
Therapuetic Areas:Dermatology / Plastic Surgery, Otolaryngology
Healthy:No
Age Range:18 - Any
Updated:3/27/2019
Start Date:March 15, 2018
End Date:September 2020
Contact:Menlo Study Director
Email:nularis3@menlotx.com
Phone:650-486-1416

Use our guide to learn which trials are right for you!

An Open-Label Long-Term Safety Study of Serlopitant for the Treatment of Pruritus

Study of the long term safety of serlopitant for the treatment of pruritus in adults.


Inclusion Criteria:

- Male or female, age 18 years or older at consent.

- Pruritus associated with prurigo nodularis, atopic dermatitis, or psoriasis.

- Female subjects of childbearing potential must be willing to practice highly effective
contraception until 5 weeks after last dose of study drug.

- Willing and able to comply with study visits and study related requirements including
providing written informed consent.

Exclusion Criteria:

- Malignancy within 5 years prior to enrollment (exception for non-melanoma cutaneous
malignancies).

- Any known major psychiatric diagnosis, such as major depressive disorder, bipolar
disorder, schizophrenia, psychotic disorder, intellectual disability, severe alcohol
use disorder, which may confound the assessment of serlopitant safety or efficacy, or
interfere with the subject's ability to comply with protocol-mandated activities,
within 3 years prior to enrollment.

- Untreated or inadequately treated thyroid, adrenal, or pituitary nodules or disease,
or history of thyroid malignancy; or the prescense of any medical condition or
disability, that could interfere with the assessment of safety in this study or
compromise the safety of the subject.

- Investigational therapy within 4 weeks or 5-half-lives prior to enrollment (whichever
is longer) or expected participation in another clinical study involving an
investigational product or device during the subject's participation in this study.

- Treatment with other neurokinin-1 receptor (NK1-R) antagonists (e.g., aprepitant,
fosaprepitant, rolapitant) within 4 weeks.

- Treatment with strong cytochrome P450 3A4 inhibitors within 4 weeks.

- Currently pregnant or breastfeeding or planning to become pregnant during the study.
We found this trial at
41
sites
Richmond, Virginia 23298
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Ann Arbor, Michigan 48103
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
Austin, Texas
?
mi
from
Austin, TX
Click here to add this to my saved trials
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
Bellaire, Texas 77401
?
mi
from
Bellaire, TX
Click here to add this to my saved trials
Bexley, Ohio 43209
?
mi
from
Bexley, OH
Click here to add this to my saved trials
Brooklyn, New York 11215
?
mi
from
Brooklyn, NY
Click here to add this to my saved trials
Bryant, Arkansas 72022
?
mi
from
Bryant, AR
Click here to add this to my saved trials
Buffalo, New York 14215
?
mi
from
Buffalo, NY
Click here to add this to my saved trials
Cleveland, Ohio 44142
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Coral Gables, Florida 33134
?
mi
from
Coral Gables, FL
Click here to add this to my saved trials
Dallas, Texas 75216
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Detroit, Michigan 48202
?
mi
from
Detroit, MI
Click here to add this to my saved trials
Dublin, Ohio 43016
?
mi
from
Dublin, OH
Click here to add this to my saved trials
761 New Jersey 33
East Windsor, New Jersey 08520
?
mi
from
East Windsor, NJ
Click here to add this to my saved trials
Fremont, California 94538
?
mi
from
Fremont, CA
Click here to add this to my saved trials
Fridley, Minnesota 55432
?
mi
from
Fridley, MN
Click here to add this to my saved trials
Glenn Dale, Maryland 20769
?
mi
from
Glenn Dale, MD
Click here to add this to my saved trials
?
mi
from
Graz,
Click here to add this to my saved trials
Henderson, Nevada 89052
?
mi
from
Henderson, NV
Click here to add this to my saved trials
High Point, North Carolina 27262
?
mi
from
High Point, NC
Click here to add this to my saved trials
Houston, Texas 77004
?
mi
from
Houston, TX
Click here to add this to my saved trials
Johnston, Rhode Island
?
mi
from
Johnston, RI
Click here to add this to my saved trials
Knoxville, Tennessee 37317
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
Louisville, Kentucky 40202
?
mi
from
Louisville, KY
Click here to add this to my saved trials
New Orleans, Louisiana 70112
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
New York, New York 10029
?
mi
from
New York, NY
Click here to add this to my saved trials
Newnan, Georgia 30263
?
mi
from
Newnan, GA
Click here to add this to my saved trials
North Hollywood, California
?
mi
from
North Hollywood, CA
Click here to add this to my saved trials
North Miami Beach, Florida 33162
?
mi
from
North Miami Beach, FL
Click here to add this to my saved trials
Omaha, Nebraska 68144
?
mi
from
Omaha, NE
Click here to add this to my saved trials
Orange Park, Florida 32073
?
mi
from
Orange Park, FL
Click here to add this to my saved trials
Pflugerville, Texas
?
mi
from
Pflugerville, TX
Click here to add this to my saved trials
Pittsburgh, Pennsylvania 15212
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
Saint Joseph, Missouri
?
mi
from
Saint Joseph, MO
Click here to add this to my saved trials
San Antonio, Texas
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
San Diego, California 92103
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Santa Ana, California 92701
?
mi
from
Santa Ana, CA
Click here to add this to my saved trials
Spartanburg, South Carolina
?
mi
from
Spartanburg, SC
Click here to add this to my saved trials
Tulsa, Oklahoma 74136
?
mi
from
Tulsa, OK
Click here to add this to my saved trials
Webster, Texas 77598
?
mi
from
Webster, TX
Click here to add this to my saved trials