Localization of Peripheral Pulmonary Lesions: A Pilot Study
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 5/30/2018 |
| Start Date: | April 30, 2018 |
| End Date: | April 30, 2019 |
| Contact: | Alexander Chen, M.D. |
| Email: | chenac@wustl.edu |
| Phone: | 314-454-8764 |
Despite technological advancements directed towards the diagnosis of peripheral pulmonary
lesions, an optimal approach has yet to be designed. One significant barrier for the
bronchoscopic biopsy of peripheral lesions is the ability to reliably locate peripheral
lesions in an efficient manner. The majority of the published literature regarding peripheral
lesion biopsy has used diagnostic yield as the primary endpoint. Based on this data, it is
unclear if non-diagnostic procedures are due to the inability to locate peripheral lesions,
or due to the inability to successfully biopsy lesions once located using currently available
instruments. This study will evaluate the bronchoscopists' ability to locate peripheral
pulmonary lesions by using a conventional chest computed tomography (CT) scan as a reference
and a virtual bronchoscopic navigational system, if needed, for the localization of
peripheral pulmonary lesions.
lesions, an optimal approach has yet to be designed. One significant barrier for the
bronchoscopic biopsy of peripheral lesions is the ability to reliably locate peripheral
lesions in an efficient manner. The majority of the published literature regarding peripheral
lesion biopsy has used diagnostic yield as the primary endpoint. Based on this data, it is
unclear if non-diagnostic procedures are due to the inability to locate peripheral lesions,
or due to the inability to successfully biopsy lesions once located using currently available
instruments. This study will evaluate the bronchoscopists' ability to locate peripheral
pulmonary lesions by using a conventional chest computed tomography (CT) scan as a reference
and a virtual bronchoscopic navigational system, if needed, for the localization of
peripheral pulmonary lesions.
Inclusion Criteria:
- Patients with peripheral lung lesions 1-5cm in size identified on chest CT with the
intention to undergo bronchoscopic evaluation and biopsy. The decision to pursue
biopsy will be made by the treating physician and agreed upon by the patient.
- Are at least 18 years old
- Are able to provide informed consent
- Have CT scans within 30 days suitable for use with the virtual bronchoscopic system
Exclusion Criteria:
- Patients who refuse to participate
- Are less than 18 years of age
- Are pregnant
- Are physically unable to tolerate flexible bronchoscopy or moderate sedation as
determined by the bronchoscopist
- Are unable to provide informed consent
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Principal Investigator: Alexander Chen, M.D.
Phone: 314-454-8764
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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