Cognitive Control Training for Urgency in a Naturalistic Clinical Setting



Status:Enrolling by invitation
Conditions:Psychiatric, Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - Any
Updated:9/16/2018
Start Date:September 4, 2018
End Date:February 2021

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A Randomized Controlled Trial of Cognitive Control Training for Urgency in a Naturalistic Clinical Setting

This study is designed to test whether computer-based cognitive exercises are helpful for
reducing a specific type of impulsivity. Also, the study is testing whether these are
exercises are associated with specific changes in behavior and in the brain. Participants
will be psychiatric patients enrolled in a partial hospitalization program. Half of these
participants will receive usual treatment, and half will complete computer-based cognitive
exercises in addition to usual treatment.

Impulsivity has different components. One personality trait related to impulsivity, known as
"urgency," is strongly related to many different mental health symptoms and risky behaviors.
Urgency refers to impulsivity specifically in the context of strong emotions.

Research shows that higher levels of urgency are related to specific deficits in cognition.
Problems with response inhibition--the ability to cancel or withhold a planned action--are
associated with urgency. Also, research shows that difficulties in another aspect of
cognition--working memory--may moderate the relationship between inhibition deficits and
urgency. One previous study found that people who practiced computerized response inhibition
and working memory tasks for two weeks reported significant decreases in urgency.

It is unknown if these computerized tasks would be helpful for reducing urgency in adults
with psychiatric disorders. Furthermore, it is unknown if changes in urgency are related to
changes in the brain mechanisms that help to support response inhibition. This study will
collect data on brain activity while people are completing response inhibition tasks.

Inclusion Criteria:

- Currently receiving treatment at the McLean Hospital Behavioral Health Partial
Hospital Program (PHP)

- Report an average score of 3.0 or greater on the Negative Urgency scale, the Positive
Urgency scale, or 3.0 or greater on both scales, upon admission to the PHP

- Right-handed (if enrolled in EEG arm)

Exclusion Criteria:

- Currently undergoing electroconvulsive therapy (ECT)

- Current symptoms of acute mania

- Current symptoms of acute psychosis

- History of traumatic brain injury
We found this trial at
1
site
115 Mill St
Belmont, Massachusetts 02478
(617) 855-2000
McLean Hospital McLean Hospital is a comprehensive psychiatric hospital committed to providing easy access to...
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Belmont, MA
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