Carbon Monoxide Blood and DNA Biorepository



Status:Enrolling by invitation
Conditions:Other Indications
Therapuetic Areas:Other
Healthy:No
Age Range:18 - Any
Updated:5/6/2018
Start Date:February 2012
End Date:December 2020

Use our guide to learn which trials are right for you!

Carbon Monoxide Blood and DNA Repository

The purpose of this biorepository is to collect blood from patients at the time of CO
poisoning and at follow-up visits months to years later. These samples can be used in the
future to learn more about how CO damages the heart and brain and whether blood tests could
predict which patients will have problems after CO poisoning.

The investigators propose to establish a biorepository for storage of serum, plasma, and DNA
collected from patients with carbon monoxide (CO) poisoning. Participants will also be
evaluated for clinical outcome. The biorepository will include serum and plasma from
CO-poisoned patients drawn at the time of injury as well as from blood drawn at clinical
follow-up visits. The biorepository will also bank DNA from these participants.

These specimens can be analyzed in the future to elucidate potential inflammatory and
immunological mechanisms that cause brain and heart damage and identify possible biological
and genetic predictors of poor outcome.

Inclusion Criteria:

1. Symptomatic carbon monoxide poisoning (headache, nausea, vomiting, dizziness, fatigue,
muscle aches, slowed mentation, confusion, loss of consciousness, etc.).

2. Documented exposure to carbon monoxide and no other reasonable explanation for their
signs and symptoms.

Exclusion criteria:

1. Pregnancy

2. Age < 18 years

3. Unable to obtain informed consent

4. Subjects who, in the opinion of the investigator, are unable to comply with the
requirements of the study or are unsuitable for any reason. The investigator and the
Sponsor, prior to enrolling the subject on a case-by-case basis, must approve and
document any waiver of these inclusion and exclusion criteria.

5. Anemia requiring blood products within the last 4 months or hematocrit less than the
laboratory normal reference range
We found this trial at
2
sites
5121 S Cottonwood St
Murray, Utah 84157
(801) 507-7000
Intermountain Medical Center Intermountain Medical Center is one of the most technologically advanced and patient-friendly...
?
mi
from
Murray, UT
Click here to add this to my saved trials
8th Ave & C St
Salt Lake City, Utah 84143
(801) 408-1100
LDS Hospital LDS Hospital provides clinical excellence to our community in a wide range of...
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials