Prevention of Skeletal Muscle Adaptations to Traumatic Knee Injury and Surgery
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 5/5/2018 |
| Start Date: | October 2016 |
| End Date: | August 2018 |
| Contact: | Rebecca Choquette, AT |
| Email: | rebecca.choquette@uvm.edu |
| Phone: | 656-2252 |
Traumatic knee injury is common and highly debilitating. Surgical reconstruction/repair
improves knee biomechanics and function, but neuromuscular dysfunction persist for years
despite rehabilitation, hindering resumption of normal activities, increasing risk of further
injury and, in a majority of patients, hastening the development of knee osteoarthritis (OA).
Our goal in this research study is to evaluate the utility of neuromuscular electrical
stimulation (NMES), initiated following injury and maintained through the early post-surgical
period, to prevent muscle atrophy and intrinsic contractile dysfunction compared to active
control intervention of micro-electrical stimulation.
improves knee biomechanics and function, but neuromuscular dysfunction persist for years
despite rehabilitation, hindering resumption of normal activities, increasing risk of further
injury and, in a majority of patients, hastening the development of knee osteoarthritis (OA).
Our goal in this research study is to evaluate the utility of neuromuscular electrical
stimulation (NMES), initiated following injury and maintained through the early post-surgical
period, to prevent muscle atrophy and intrinsic contractile dysfunction compared to active
control intervention of micro-electrical stimulation.
Inclusion Criteria:
- 18-50 yrs
- BMI <35 kg/m2
- acute, first-time, ACL rupture with or without meniscus injury
- scheduled to undergo reconstruction with a BPTB autograft
Exclusion Criteria:
- history of prior knee/lower extremity surgery or non-surgical intervention (eg,
intra-articular injection) on either leg
- abnormal laxity of any lower extremity ligament other than the injured ACL
- signs or symptoms of arthritis, autoimmune or inflammatory disease or diabetes
- grade IIIb or greater articular cartilage lesions (ICRS criteria)
- women who are/plan on becoming pregnant
We found this trial at
1
site
1 South Prospect Street
Burlington, Vermont 05401
Burlington, Vermont 05401
802-656-8990
Phone: 802-656-2252
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