Half-normal Saline in Idiopathic Left Ventricular Outflow Tract Arrhythmias Ablation

Status:	Recruiting
Healthy:	No
Age Range:	18 - 75
Updated:	2/8/2019
Start Date:	May 16, 2018
End Date:	May 2020

Half-normal Saline vs Normal Saline for Irrigation of Open-irrigated Radiofrequency Catheters in Idiopathic Left Ventricular Outflow Tract Arrhythmias Ablation

The study evaluates the use of half-normal saline as an irrigant for open-irrigated catheters
during left ventricular outflow tract ventricular arrhythmias ablation. By increasing the
efficacy of radiofrequency energy-mediated lesion formation, half-normal saline has the
potential to reduce procedural times and improved acute and long-term outcomes.

Inclusion criteria

- male or female between 18 and 75 years of age at the time of enrollment

- undergoing first-time radiofrequency ablation for left ventricular outflow tract
ventricular arrhythmias

- written informed consent obtained from subject or subject's legal representative and
ability for subject to comply with the requirements of the study

Exclusion criteria

- ventricular arrhythmias originating from the right ventricular outflow tract according
to the ventricular arrhythmia ECG morphology (i.e., precordial R wave transition at V3
or later)

- ventricular arrhythmias not originating from cardiac outflow tracts

- baseline hyponatremia (serum sodium level < 135 mEq/L)

- pregnant, breastfeeding, or unwilling to practice birth control during participation
in the study

- presence of a condition or abnormality that in the opinion of the Investigator would
compromise the safety of the patient or the quality of the data

We found this trial at

sites

Texas Cardiac Arrhythmia Institute, St. David's Medical Center

Austin, Texas 78705

Phone: 512-544-8186

from

Austin, TX