Can Individuals Control Pressure in Their Esophagus.



Status:Not yet recruiting
Conditions:Gastroesophageal Reflux Disease
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - Any
Updated:4/17/2018
Start Date:May 1, 2018
End Date:July 30, 2018
Contact:Christopher J Yelvington, DPT
Email:yelvington.c@mayo.edu
Phone:8502064596

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Subjects Ability to Control Pressure in the Lower Esophageal High Pressure Znoe (HPZ) During Manometry.

To establish to what degree individuals can increase esophageal high pressure zone (HPZ)
after instruction in deep breathing as evidenced by concurrent manometric pressure readings.

Pressure in the lower esophagus has been negatively associated with reflux symptoms: the
lower the pressure, the more reflux symptoms. This pressure can be augmented with deep
abdominal breathing. This can be detected during esophageal manometry, when a pressure
catheter is placed into the esophagus. Manometry is routinely done for swallowing disorders.

This study will take place just after a routine manometry test, when the subject still has
the catheter in place. All that is required for the research portion is to observe manometry
readings while they breathe, then when they deep breath, then breathe after they have been
cued or coached to deep abdominal breathing. This is done in sequence to establish how
quickly this pressure can be improved.

This coached breathing is then prescribed as a routine exercise and long term follow up
performed via phone to see how their reflux symptoms have responded.

Inclusion Criteria:

-Eligibility is forwarded to all individuals undergoing routine esophageal manometry. They
would have had to have met all eligibility criteria for this procedure.

Exclusion criteria:

-Individuals undergoing modified barium swallow studies (MBSS). Exclusion from MBSS would
preclude inclusion in this study.
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