Improving Learning in Hispanics With TBI or MS



Status:Recruiting
Conditions:Neurology, Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 65
Updated:7/5/2018
Start Date:September 25, 2013
End Date:September 30, 2020
Contact:Denise Krch, PhD
Email:dkrch@kesslerfoundation.org
Phone:973-324-8392

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Improving Learning in Hispanics With TBI or MS: A Pilot Trial

The goal of this study is to establish that a memory retraining protocol, originally
developed for English-speakers, and translated into Spanish, is effective.

A pilot study will be conducted to carry out this validation and resolve any methodological
concerns in the translated protocol. 20 Spanish-speaking Hispanics at least one year
post-traumatic brain injury (TBI) and 20 Spanish-speaking Hispanics with multiple sclerosis
(MS), both with an objective deficit in learning and memory will be recruited. Baseline
assessment includes neuropsychological evaluation using traditional measures as well as
completion of a number of questionnaires designed to measure everyday memory and everyday
functioning. Subjects are randomly assigned to either the experimental or control groups.
Experimental and control treatments includes two 45-60 minute sessions, twice per week, for 5
weeks. Follow-up assessment includes a neuropsychological evaluation using traditional
measures as well as completion of a number of questionnaires designed to measure everyday
memory and everyday functioning. Protocol efficacy will be determined by improvements between
baseline and follow-up on an objective measure of learning and memory.

Inclusion Criteria:

- between the ages of 18 and 65

- Spanish is my dominant language, and I have had a traumatic brain injury or I have
multiple sclerosis.

Exclusion Criteria:

- Participants with major depressive disorder, schizophrenia, bipolar disorder I or II

- MS subjects: Individuals with a history of head injury, stroke, seizures, or any other
significant neurological history will not be included in the study.

- TBI subjects: Individuals must have sustained a TBI at least one year prior to
enrollment in the study protocol. Individuals with a history of significant
neurological insult other than TBI (e.g. premorbid epilepsy, multiple sclerosis,
Alzheimer's disease) will not be included in the study.
We found this trial at
2
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120 Eagle Rock Avenue
East Hanover, New Jersey 07936
Phone: 973-324-8392
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Arrasate-Mondragón,
Phone: +34 943794411
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