Using Breath Metabolites to Determine Specific Virus Infection in Asthmatic Patients
| Status: | Recruiting |
|---|---|
| Conditions: | Infectious Disease, Infectious Disease, Pulmonary |
| Therapuetic Areas: | Immunology / Infectious Diseases, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 12 - Any |
| Updated: | 4/17/2018 |
| Start Date: | February 1, 2017 |
| End Date: | June 2019 |
| Contact: | Michael Schivo, MD, MAS |
| Email: | mschivo@ucdavis.edu |
| Phone: | (916) 734-3564 |
Respiratory virus infections cause a majority of asthma exacerbations in the fall to spring
months. Current diagnostic platforms for respiratory viruses have limitations including cost,
availability, and invasiveness. The use of noninvasive breath collection to analyze breath
metabolites may be used to differentiate virus-infected asthmatics from other causes of acute
asthma exacerbations.
months. Current diagnostic platforms for respiratory viruses have limitations including cost,
availability, and invasiveness. The use of noninvasive breath collection to analyze breath
metabolites may be used to differentiate virus-infected asthmatics from other causes of acute
asthma exacerbations.
Inclusion Criteria:
- Asthma, Age ≥12, Symptoms/signs of an early asthma exacerbation, Ability to provide
exhaled breath condensate (EBC) x15 min, Body mass index (BMI) ≥18
Exclusion Criteria:
- Chronic lung diseases other than asthma (e.g., chronic obstructive pulmonary disease
[COPD], lung cancer, fibrotic lung disease, etc.), Smoking in the past 7 days, Eating
or non-clear liquids <4 hrs prior to EBC collection, Pregnancy
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