Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's Disease
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Alzheimer Disease, Cognitive Studies, Cognitive Studies |
| Therapuetic Areas: | Neurology, Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 55 - Any |
| Updated: | 3/10/2019 |
| Start Date: | May 21, 2014 |
| End Date: | January 2025 |
Participants enrolled in the Alzheimer's Disease Clinical Core at Wake Forest School of
Medicine will be invited to take part in this study. The purpose of this study is to identify
and measure the amount of a protein called amyloid in the brain.It is thought that the build
up of amyloid may be related to the development of Alzheimer's disease.
Medicine will be invited to take part in this study. The purpose of this study is to identify
and measure the amount of a protein called amyloid in the brain.It is thought that the build
up of amyloid may be related to the development of Alzheimer's disease.
Brain amyloid will be measured using PET with [11C]PiB. Participation will involve an initial
brain scan and possibly a follow-up brain scan two years later.
The data collected in this study will help explain amyloid deposits in several groups of
participants including adults with and without signs of memory impairment. The information
collected will help find out who is more likely to have brain amyloid and when it increases
the risk for developing memory problems. Research studies suggest that people with elevated
levels of brain amyloid are at an increased risk for memory decline, but this does not mean
that every person with amyloid build up will develop AD.
brain scan and possibly a follow-up brain scan two years later.
The data collected in this study will help explain amyloid deposits in several groups of
participants including adults with and without signs of memory impairment. The information
collected will help find out who is more likely to have brain amyloid and when it increases
the risk for developing memory problems. Research studies suggest that people with elevated
levels of brain amyloid are at an increased risk for memory decline, but this does not mean
that every person with amyloid build up will develop AD.
Inclusion Criteria:
- Enrolled in the Alzheimer's Disease Clinical Core
Exclusion Criteria:
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