Effect of a Fatty Meal on Endoscopic Retrograde Cholangiopancreatography (ERCP)



Status:Recruiting
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - Any
Updated:7/16/2013
Start Date:May 2003
Contact:Qiang Cai, MD, PhD
Email:qcai@emory.edu
Phone:404-778-4857

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Effect of a Fatty Meal on Cannulation at Endoscopic Retrograde Cholangiopancreatography


This study is to determine if a fatty meal would improve the ERCP procedure.


A fatty meal is a potent stimulator of cholecystikinin (CCK) in human body. The biological
effect of CCK is increasing bile secretion and relaxing the sphincter of Oddi.
Theoretically, a fatty meal should facilitate the effect on cannulation at ERCP. If a fatty
meal can make the major papilla cannulation easier, it may significantly shorten the
procedure time for ERCP and even decrease complications of the procedure, since the
complication rate of post-ERCP is positively related to the time of the procedure.

Comparison: Approximately one hour before ERCP procedure, patient will have a fatty meal in
the study group and normal saline in control group.

Inclusion Criteria:

- Patients, 18 years and older, who are scheduled for ERCP at Emory University Hospital
and signed consent before the procedure.

Exclusion Criteria:

- Patients with a known allergy to milk or those who choose not to sign the consent.
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