Evaluation of a New MR Pulse Sequence to Quantify Liver Iron Concentration
| Status: | Completed |
|---|---|
| Conditions: | Hematology |
| Therapuetic Areas: | Hematology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | August 2003 |
| End Date: | July 2011 |
The purpose of this study is to determine if a new MR pulse sequence is accurate in
determining how much iron is in the liver.
determining how much iron is in the liver.
Quantification of liver iron requires liver biopsy and histological assessment. New rapid MR
techniques allow determination of liver relaxation times that can be altered with increasing
iron deposition. The purpose of this study is to compare the results obtained with MRI to
liver biopsy and iron quantification in patients undergoing liver biopsy in the setting of
hemochromatosis.
techniques allow determination of liver relaxation times that can be altered with increasing
iron deposition. The purpose of this study is to compare the results obtained with MRI to
liver biopsy and iron quantification in patients undergoing liver biopsy in the setting of
hemochromatosis.
Inclusion Criteria:
- Undergoing liver biopsy for suspected or known hemochromatosis
- Undergoing liver biopsy for living-related liver donation evaluation
Exclusion Criteria:
- Contraindication to MRI
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