Percent Change in Baseline Bone Mineral Density (BMD) After Parathyroidectomy in Patients With Primary Hyperparathyroidism



Status:Recruiting
Conditions:Endocrine
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:Any
Updated:2/16/2018
Start Date:September 3, 2014
End Date:September 2020
Contact:Nancy D. Perrier, MD
Phone:713-792-6940

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The primary objective of this study is to estimate the percent change in baseline bone
mineral density (BMD) starting at one year after parathyroidectomy and all the following
available dates in patients presenting with primary hyperparathyroidism. The secondary
objective is to identify patient factors associated with change in BMD.

The research plan is for a retrospective review to be performed of a prospectively maintained
parathyroid database within the Department of Surgical Oncology at the University of Texas MD
Anderson Cancer Center. The patient cohort for this study consists of all patients with
primary hyperparathyroidism who underwent parathyroidectomy and also had pre- and
post-operative DEXA studies performed. The database will be reviewed to obtain patient and
disease characteristics, laboratory values, DEXA imaging results, and surgical outcomes.

Inclusion Criteria:

1. The patient cohort for this study consists of all patients within the prospectively
maintained parathyroid database within the Department of Surgical Oncology at the
University of Texas MD Anderson Cancer Center.

2. Patients with a diagnosis of primary hyperparathyroidism who underwent
parathyroidectomy during the period of September 27, 1990 to December 31, 2013 were
considered.

3. All patients who had a preoperative and one year post-operative DEXA study over the
time period will be included.

Exclusion Criteria:
We found this trial at
1
site
1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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Houston, TX
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