Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 2



Status:Recruiting
Conditions:Smoking Cessation, Tobacco Consumers
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 20
Updated:2/15/2018
Start Date:May 2, 2017
End Date:August 2018
Contact:Healther LaVallee, B.A.
Email:heather.lavellee@yale.edu
Phone:203-974-7373

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This study is to examine if inhaled doses of an e-cigarette flavor, alone and in combination
with menthol, changes the appeal of e-cigarettes containing low and high doses of nicotine.
The hypothesis is that menthol and the other experimental flavor will interact with nicotine
dose to improve taste and liking for e-cigarettes.


Inclusion Criteria:

- Ages 18-20 years

- Able to read and write

- Urine cotinine levels of >250 ng/ml at screening appointment

- Use of e-cigarettes in the past month

- May or may not currently smoke traditional cigarettes

Exclusion Criteria:

- Seeking smoking cessation treatment

- Current/lifetime criteria for dependence on another psychoactive substance -Daily use
of alcohol or marijuana or use of any other drugs including cocaine, opiates,
stimulants

- Regular use of psychoactive drugs including anxiolytics, antidepressants and other
psychostimulants

- Current or past history of psychosis or other psychiatric diagnosis such as major
depression

- Any significant current medical condition
We found this trial at
1
site
New Haven, Connecticut 06519
Principal Investigator: Suchitra Krishnan-Sarin, Ph.D.
Phone: 203-974-7607
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from
New Haven, CT
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