Study to Evaluate the Effect of Secukinumab Compared to Placebo on Aortic Vascular Inflammation in Subjects With Moderate to Severe Plaque Psoriasis



Status:Completed
Conditions:Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - Any
Updated:10/7/2018
Start Date:February 10, 2016
End Date:February 19, 2018

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A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Effect of Secukinumab on Aortic Vascular Inflammation and Cardiometabolic Biomarkers After 12 Weeks of Treatment, Compared to Placebo, and up to 52 Weeks of Treatment With Secukinumab in Adult Subjects With Moderate to Severe Chronic Plaque-type Psoriasis

This study evaluated the effect of secukinumab compared to placebo on aortic vascular
inflammation in adult patients who have moderate to severe plaque psoriasis that is poorly
controlled by current psoriasis treatments.


Inclusion Criteria:

- Males and females at least 18 years of age with moderate to severe plaque psoriasis

Exclusion Criteria:

- Forms of psoriasis other than chronic plaque psoriasis

- Previous exposure to IL-17A or IL-17 receptor targeting agents.

- Other active or ongoing disease that may interfere with evaluation of psoriasis or
places the patient at unacceptable risk

- Other protocol-defined inclusion/exclusion criteria may apply
We found this trial at
11
sites
Buffalo, New York 14215
2184
mi
from 91732
Buffalo, NY
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Dallas, Texas 75216
1225
mi
from 91732
Dallas, TX
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Exton, Pennsylvania 19341
2350
mi
from 91732
Exton, PA
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Houston, Texas 77030
1357
mi
from 91732
Houston, TX
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Los Angeles, California 90095
25
mi
from 91732
Los Angeles, CA
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230 Park Avenue, 21st Floor
New York, New York 10169
1-888-669-6682)
Novartis Novartis, which was created in 1996 by the merger of the Swiss companies Ciba-Geigy...
2435
mi
from 91732
New York, NY
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Portland, Oregon 97228
Novartis Novartis, which was created in 1996 by the merger of the Swiss companies Ciba-Geigy...
829
mi
from 91732
Portland, OR
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Rockville, Maryland 20852
2275
mi
from 91732
Rockville, MD
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Saint Louis, Missouri 63128
1562
mi
from 91732
Saint Louis, MO
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Salt Lake City, Utah 84103
570
mi
from 91732
Salt Lake City, UT
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Santa Ana, California 92705
24
mi
from 91732
Santa Ana, CA
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