Multi-Organ Screening Recommendations in Patients With Lynch Syndrome



Status:Recruiting
Conditions:Colorectal Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:9/22/2018
Start Date:December 2004
End Date:December 2019
Contact:Zsofia Stadler, MD
Phone:646-888-4083

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Adherence to Comprehensive, Multi-Organ Screening Recommendations in Patients With Lynch Syndrome

The purpose of this study is to examine how people with a family history of colon cancer and
other related cancers respond to recommendations for cancer screening after genetic
counseling. The purpose of your participation would be to help us learn more about whether
people with a personal and/or family history of colorectal cancer and other cancers follow
cancer screening recommendations.


Inclusion Criteria:

- A patient will be eligible for enrollment if he/she is self-referred or
physician-referred for genetic counseling at Memorial Sloan-Kettering Cancer Center's
(MSKCC) Clinical Genetics Service due to a concern about increased risk for colon
cancer or;

- An individual who presents for genetic counseling at MSKCC's Clinical Genetics Service
after undergoing genetic testing at an outside institution with a documented mutation
in any gene associated with Lynch Syndrome or;

- An individual who in the context of genetic counseling has received stricter
colorectal and/or gynecologic screening recommendations than that of the general
population regardless of genetic test results.

- DNA of patients who have been consented to protocol 93-102 ("Ascertainment of
Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial
Cancers"), who meet the eligibility criteria listed above, will also be eligible for
inclusion in this study.

Exclusion Criteria:

- Patients will be excluded from this study if: he/she has physical, cognitive or
psychiatric conditions that interfere with ability to give meaningful informed
consent; he/she cannot read, write or communicate in English; he/she is less than 18
years of age; he/she has received a diagnosis of FAP.
We found this trial at
9
sites
500 Westchester Avenue
Harrison, New York 10604
Phone: 646-888-4083
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136 Mountainview Boulevard
Basking Ridge, New Jersey 07920
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Commack, New York 11725
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Hauppauge, New York 11788
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480 Red Hill Road
Middletown, New Jersey 07748
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225 Summit Avenue
Montvale, New Jersey 07645
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1275 York Ave
New York, New York 10021
(212) 639-2000
Principal Investigator: Zsofia Stadler, MD
Phone: 646-888-4615
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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1275 York Avenue
Rockville Centre, New York 11570
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Rockville Centre, NY
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Sleepy Hollow, New York 10591
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