Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty



Status:Recruiting
Conditions:Arthritis, Osteoarthritis (OA)
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - 95
Updated:3/15/2019
Start Date:March 4, 2019
End Date:September 2019
Contact:Christopher J Edwards, MD
Email:chedward@wakehealth.edu
Phone:3367168222

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Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty: A Non-inferiority Trial

Total hip arthroplasty (THA) is one of the most successful orthopedic procedures to
effectively relieve pain and restore function in patients with end stage osteoarthritis. In
an attempt to accelerate recovery many orthopedic surgeons have opted to utilize a direct
anterior approach (DAA) as opposed to the more traditional posterolateral approach (PLA). The
literature supports that DAA is superior to PLA with regard to lower blood loss, less pain,
shorter hospital stay, and faster rehabilitation. Traditionally the study team has performed
Lumbar Plexus blocks (LPB) to provide post-operative analgesia for total hip arthroplasty.
The quadratus lumborum block (QLB) is a newer regional analgesic technique that may be as
effective as LPB at providing pain control following DAA hip arthroplasty. This study is
designed to compare the efficacy, with regards to post-operative pain management, between LPB
and QLB following a DAA total hip arthroplasty.

In an attempt to accelerate recovery many orthopedic surgeons have opted to utilize a direct
anterior approach (DAA) as opposed to the more traditional posterolateral approach (PLA) in
regards to total hip arthroplasty (THA). The DAA technique involves dissection of muscular
planes for insertion of components resulting in less tissue damage as compared to PLA.
Traditionally the study team has performed Lumbar Plexus blocks (LPB) to provide
post-operative analgesia for total hip arthroplasty. This technique works well for the
traditionally performed PLA in that the hip joint and incision site are within the analgesic
distribution of the LPB. Conversely, the DAA utilizes an anterior incision that overlies the
L1 and L2 dermatomes as opposed to the lower lumbar dermatomes of the PLA incision. When
performing LPB it has been the study team's clinical experience that it is rare to achieve
analgesia in the proximal distribution of the lumbar plexus resulting in apparent sparing of
the L1 and L2 nerve root distributions. The quadratus lumborum block (QLB) is a newer
regional analgesic technique that may be as effective as LPB at providing pain control
following DAA hip arthroplasty. The QLB is thought to provide analgesia by blocking both the
lateral and anterior cutaneous branches of T7 through L4. This degree of dermatomal coverage
suggests that QLB could be an efficacious alternative to LPB for DAA hip arthroplasty. It is
hypothesized that the QLB will provide equivalent analgesia when compared to the LPB as
determined by a comparison of verbal reported pain scores.

Inclusion Criteria:

- Any patient between the ages of 18 and 95 years undergoing a primary elective,
unilateral DAA total hip arthroplasty.

Exclusion Criteria:

- If the patient uses more than 40mg of Oxycodone equivalents per 24 hours or is on
extended release opioid formulations.

- Indication for surgery is secondary to trauma and/or hip fracture

- If there is a contraindication to the performance of a regional block

- Concomitant anticoagulation use or documented coagulopathy

- Infectious or dermatologic conditions in the area of block placement that would
otherwise increase the risk of peripheral nerve blockade

- Presence of progressive neurologic deficit effecting peripheral nerves

- Allergy or adverse reaction to study drugs to include: fentanyl, epinephrine, and
amide local anesthetics

- American Society of Anesthesia Physical Classification score > or = to 4

- Allergies to study drugs other than local anesthetic

- BMI > 40

- Patient refusal

- Pregnancy

- Institutionalized individuals

- Extremes of age: Age > 95 or < 18

- Non English speaking or inability to reliably participate in the study
We found this trial at
1
site
Winston-Salem, North Carolina 27157
Phone: 336-716-8222
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Winston-Salem, NC
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