Treatment of Exercise-Induced Pulmonary Vascular Dysfunction in Symptomatic Patients After Pulmonary Thromboendarterectomy



Status:Not yet recruiting
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 100
Updated:1/6/2019
Start Date:April 2019
End Date:May 2020
Contact:Cheri Abbott, RN
Email:Cheryl.Abbott@ucdenver.edu
Phone:303-724-7466

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This is an open label study of Riociguat in patients with continued exercise intolerance at
least 6 months following pulmonary endarterectomy (PEA).


Inclusion Criteria:

- Adult patients who underwent PTE for Chronic thromboembolic pulmonary hypertension
(CTEPH) at least six months prior to screening and report ongoing subjective exercise
limitation,

- able to give consent

- able to perform a exercise protocol

Exclusion Criteria:

- Patients with known Residual Pulmonary Hypertension (RPH) by RHC following PTE for
CTEPH

- ongoing PAH-specific vasodilator therapy

- known contraindication to riociguat

- a physical limitation to completing an exercise protocol
We found this trial at
1
site
13001 E 17th Pl
Aurora, Colorado 80045
(303) 724-5000
Principal Investigator: Todd Bull, MD
Phone: 303-724-7466
University of Colorado Anschutz Medical Campus Located in the Denver metro area near the Rocky...
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Aurora, CO
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