Exercise and Rehabilitation After Traumatic Brain Injury
| Status: | Recruiting |
|---|---|
| Conditions: | Hospital, Neurology |
| Therapuetic Areas: | Neurology, Other |
| Healthy: | No |
| Age Range: | 18 - 60 |
| Updated: | 2/1/2018 |
| Start Date: | June 2016 |
| End Date: | March 2022 |
| Contact: | Grace S Griesbach, PhD |
| Email: | researchcentre@neuroskills.com |
| Phone: | (818)783-3800 |
Effects of Aerobic Exercise and Rehabilitation After Traumatic Brain Injury
The purpose of this study is to examine the effects of exercise on recovery after traumatic
brain injury. Investigators will determine if exercise enhances rehabilitation by increasing
substances (proteins) that can facilitate recovery.
brain injury. Investigators will determine if exercise enhances rehabilitation by increasing
substances (proteins) that can facilitate recovery.
Exercise-based therapies can promote recovery of function and are easily implemented in the
clinical rehabilitation setting. This study will determine if exercise facilitates recovery
by improving markers of neuroplasticity and decreasing neuroinflammatory responses. The
investigators will also determine if variations in genes involved in neuroplasticity, memory
and inflammation influence the responsiveness to exercise and rehabilitation. Particular
genetic polymorphisms involved in neuroplasticity and inflammatory responses will be
evaluated. Recovery will be determined by assessing cognitive function, life quality and
balance.
clinical rehabilitation setting. This study will determine if exercise facilitates recovery
by improving markers of neuroplasticity and decreasing neuroinflammatory responses. The
investigators will also determine if variations in genes involved in neuroplasticity, memory
and inflammation influence the responsiveness to exercise and rehabilitation. Particular
genetic polymorphisms involved in neuroplasticity and inflammatory responses will be
evaluated. Recovery will be determined by assessing cognitive function, life quality and
balance.
Inclusion Criteria:
- Clinical diagnosis of TBI (for R+AER and R groups).
- Fluency in English or Spanish.
- Able to walk with or without a device.
Exclusion Criteria:
- Orthopedic or cardiac conditions that prevent from exercising.
- Current diagnosis of neurological and/or psychiatric diseases.
Unable to be in the Los Angeles CA metropolitan area for the duration of the study
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