Measuring Cortisol Levels in Persons With Parkinson's (PD)
| Status: | Recruiting |
|---|---|
| Conditions: | Parkinsons Disease |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 18 - 99 |
| Updated: | 12/12/2018 |
| Start Date: | June 2016 |
| End Date: | July 2019 |
| Contact: | Brenna M Lobb, MS, MPH |
| Email: | lobbb@ohsu.edu |
| Phone: | 503.220.8262 |
The objective of this study is to evaluate the cortisol awakening response with persons with
PD and moderate levels of stress as compared to controls and persons with PD and low levels
of stress. These data are desired so experience can be gained with measuring stress levels
subjectively and objectively in persons with PD.
PD and moderate levels of stress as compared to controls and persons with PD and low levels
of stress. These data are desired so experience can be gained with measuring stress levels
subjectively and objectively in persons with PD.
Telephone consent will be obtained. Participants will collect saliva at twelve time points -
(four times a day for three days prior to their in-person visit). Participants will then have
a half-hour in-person visit at the VA to assess stress, mood, quality of life, and
Parkinson's.
(four times a day for three days prior to their in-person visit). Participants will then have
a half-hour in-person visit at the VA to assess stress, mood, quality of life, and
Parkinson's.
Inclusion Criteria:
Group (1) Inclusion:
- PD as confirmed by NINDS criteria
- PD confirmed by a movement disorders specialist
- a Perceived Stress Scale (PSS) score higher than or equal to 13.
Group (2) Inclusion:
- PD as confirmed by NINDS criteria
- PD confirmed by a movement disorders specialist
- PSS score lower than 13.
Group (3) Inclusion:
- No significant neurological disorder
- PSS score of greater than or equal to 13.
Group (4) Inclusion:
- No significant neurological disorder
- PSS score of less than 13.
Exclusion Criteria:
- The use of medications known to effect cortisol levels (estrogen, synthetic
glucocorticoids, androgens, phenytoin, spironolactone, prednisone, prednisolone, and
hydrocortisone).
We found this trial at
2
sites
Click here to add this to my saved trials
Click here to add this to my saved trials