Dyslipidemia and Diabetic Retinopathy



Status:Recruiting
Conditions:High Cholesterol, Ocular, Diabetes
Therapuetic Areas:Cardiology / Vascular Diseases, Endocrinology, Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:2/17/2019
Start Date:January 2014
End Date:January 2020
Contact:Jennifer Moorer
Email:jmoorer@uabmc.edu
Phone:205 325 8674

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The purpose of this study is to determine if the reparative cells of blood vessels called
endothelial progenitor cells(EPC) are defective in people with diabetes.

The purpose of this study is to determine if the reparative cells of blood vessels, called
endothelial progenitor cells (EPC's) are defective in people with diabetes. Diabetic
retinopathy (DR) is an eye disease related to diabetes. It can cause blurred vision and
possible bleeding in the blood vessels in the back of the eye (retina). Damage to the cells
of the blood vessels from DR can cause vision loss or blindness. Even with current
treatments, the quality of life for people with DR is much reduced.

Inclusion Criteria:

- Any man or woman

- Greater than 18 years of age

- Diagnosis of diabetes (applies to the Diabetic Arm only) (N=15 Type 1 and N=15 Type

- The subject must be willing and have the ability to cooperate with the protocol.
Children will not be eligible because the investigators need to obtain 150 ml of blood
and this is in excess of what can be drawn in children.

Exclusion Criteria:

- Female participants must not be pregnant at the time of the blood draw as evident
through a dipstick pregnancy test.

- Have retinal abnormalities other than diabetic retinopathy.
We found this trial at
1
site
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
Principal Investigator: Maria B Grant, MD, PhD.
Phone: 317-274-2628
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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mi
from
Birmingham, AL
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