Ascertainment of Saliva or Blood Samples For Genetic Epidemiology Studies of Cancer and Aging



Status:Recruiting
Conditions:Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:60 - Any
Updated:6/10/2016
Start Date:September 2006
End Date:December 2017
Contact:Kenneth Offit, MD
Phone:646-888-4067

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The purpose of this study is to help us learn more about the roles of genes in cancers.
Genes are short pieces of DNA which determine the inherited characteristics that distinguish
one individual from another. This study will look at how some genes might raise or lower the
chance some people may develop cancer. The sample collection will help generate the
materials needed for this study.

This is a protocol to obtain saliva or blood samples from non-cancer affected volunteers
aged 60 years or older, without a history of cancer other than non-melanoma skin cancer.
These samples will be used in a genomic approach to elucidate novel pathways of cancer
predisposition.

Inclusion Criteria:

- Eligible subjects must be non-cancer affected volunteers of either gender who are 60
years of age or older at the time of saliva/blood donation.

- Subjects will self-identify religion and country of origin of grandparents.

- Volunteers will have (by self report) no history of cancer other than nonmelanoma
skin cancer. It is recognized that there may be some errors in self report, however,
the literature reports a very low error rate for self reported disease reporting for
cancer as assessed by interview.

Exclusion Criteria:

- Subjects with mental impairment will be excluded from this study.
We found this trial at
1
site
1275 York Ave
New York, New York 10021
(212) 639-2000
Principal Investigator: Kenneth Offit, MD
Phone: 646-888-4067
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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