Traumatic Brain Injury and Stroke Long Term Outcome



Status:Recruiting
Conditions:Hospital, Neurology, Neurology
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:18 - Any
Updated:2/1/2018
Start Date:May 4, 2016
End Date:May 4, 2028
Contact:Grace S Griesbach, PhD
Email:researchcentre@neuroskills.com
Phone:(818)783-3800

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Effects of Rehabilitation Following Traumatic Brain Injury and Stroke: A Long Term Outcome Study.

Investigators will determine the long-lasting effects of post-acute rehabilitation after
traumatic brain injury and stroke. Investigators will also evaluate if the beneficial effects
of rehabilitation continue after discharge from a rehabilitative program.

The long-term effects of rehabilitation will be evaluated on 60 patients with traumatic brain
injury (TBI) and 60 patients that suffered a cerebrovascular accident (CVA) that underwent an
comprehensive rehabilitative. These patients will be matched with subjects that received
limited or no rehabilitation rehabilitative therapy. Thus, the total number of subjects in
this study will be 240. Subjects will be contacted at least 1 year after discharge and will
be lowed up every two-years thereafter for a total period of 10 years. Procedures will be
performed in-person whenever possible. However, it is highly likely that the majority of
participants will be contacted via phone interviews.

Aim 1: Determine if rehabilitation improves vocational status and living status after TBI and
CVA.

Aim 2: Determine if rehabilitation improves life quality after TBI and CVA.

Aim 3: Determine if rehabilitation improves cognitive function after TBI and CVA.

Aim 4: Determine if rehabilitative benefits are sustained.

Aim 5: Determine if long-term outcome is dependent on the duration of rehabilitation.

Aim 6: Determine if long-term outcome is dependent on the nature of the rehabilitative
treatment by comparing the effects of different types of rehabilitation. These will include
the following: residential-multidisciplinary, day-treatment (i.e. full time multidisciplinary
outpatient), outpatient (part-time), skilled nursing and no post-acute rehabilitation.

Inclusion Criteria:

- Endured a traumatic brain injury or stroke

- Subject or caretaker should be Fluent in English

Exclusion Criteria:

- Diagnosis of degenerative neurological disease prior to sustaining stroke or traumatic
brain injury

- b) A history of major psychosis as defined by Diagnostic and Statistical Manual of
Mental Disorders (DSM-V) prior to sustaining stroke or traumatic brain injury
We found this trial at
1
site
16542 Ventura Boulevard
Encino, California 91436
Phone: 818-783-3800
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Encino, CA
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