Effort to Prevent Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa in Mechanically Ventilated Subjects



Status:Recruiting
Conditions:Pneumonia
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 99
Updated:3/21/2019
Start Date:March 25, 2016
End Date:December 23, 2019
Contact:AstraZeneca Clinical Study Information Center
Email:information.center@astrazeneca.com
Phone:1-877-240-9479

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A Phase 2 Proof-of-concept Study to Evaluate the Efficacy and Safety of MEDI3902 in Mechanically Ventilated Patients for the Prevention of Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa

Clinical Trial looking to Evaluate the Efficacy and Safety of MEDI3902 in Mechanically
Ventilated Patients for the Prevention of Nosocomial Pneumonia Caused by Pseudomonas
aeruginosa


Inclusion Criteria:

Colonized with P aeruginosa, expected to require prolonged intubation and mechanical
ventilation, without any evidence of active pneumonia.

Exclusion Criteria:

P aeruginosa disease at randomisation; lung injury score consistent with pneumonia; current
lung disease; currently receiving protocol-specified Anti-P aeruginosa antibiotics,
moribund patients.
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