Liposomal Bupivacaine for Postoperative Pain Control in Urologic Procedures

A prospective, randomized controlled study to determine the efficacy of liposomal bupivacaine
given by local injection at all the wound sites in patients undergoing urologic surgeries.
Subjects of prospective study will be randomly divided using electronic program into two
groups:

The first group will receive intraoperative local Liposomal Bupivacaine injection at the port
placement site. The control group will receive will local Marcaine (bupivacaine HCl)
injection

Primary Outcome Measures:

- Total opioid consumption measured in intravenous morphine equivalents dose during the
postoperative hospital Stay

- Postoperative pain assessment using visual Analog Pain Scores & Brief Pain Inventory
form.

- Length of Hospital Stay

- Time to First Opioid Use.

- Postoperative Constipation , paralytic ileus

Inclusion Criteria:

- Patients undergoing urologic surgery.

Exclusion Criteria:

- Pregnant and/or nursing mothers.

- Allergy to bupivacaine.

- History of drug/alcohol abuse.

- Severe cardiovascular, hepatic, renal disease or neurological impairment.