Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations



Status:Recruiting
Healthy:No
Age Range:25 - Any
Updated:3/30/2019
Start Date:January 4, 2018
End Date:January 2021
Contact:Jada Hamilton, PhD, MPH
Email:hamiltoj@mskcc.org
Phone:646-888-0049

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The purpose of this study is to describe how women with BRCA1/2 mutations react to genetic
risk modifier testing, and to examine how they make decisions about their healthcare.


Inclusion Criteria:

- Female MSK patient, age 25 years or older (given that women under this age are not
generally recommended to receive BRCA1/2 genetic testing)

- Completed full sequence or targeted genetic testing with a clinically confirmed BRCA1
or BRCA2 deleterious mutation identified

- No personal history of breast cancer

- English-fluent; the surveys were designed and validated in English and are not
currently available in other languages. Translation of questionnaires into other
languages would require reestablishing the reliability and validity of these measures.
Therefore, participants must be able to communicate in English to complete the
surveys.

Exclusion Criteria:

- Previous receipt of any prophylactic mastectomy.

- Major psychiatric illness or cognitive impairment that in the judgment of the study
investigators or study staff would preclude study participation.

- Any patients who are unable to comply with the study procedures as determined by the
study investigators or study staff.
We found this trial at
5
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Commack, New York 11725
Phone: 646-888-0049
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Basking Ridge, New Jersey 07920
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Harrison, New York
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1275 York Ave
New York, New York 10021
(212) 639-2000
Principal Investigator: Jada Hamilton, PhD, MPH
Phone: 646-888-0049
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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Rockville Centre, New York 11570
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Rockville Centre, NY
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