Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis
| Status: | Completed |
|---|---|
| Conditions: | Arthritis, Rheumatoid Arthritis, Dental |
| Therapuetic Areas: | Dental / Maxillofacial Surgery, Rheumatology |
| Healthy: | No |
| Age Range: | 18 - 99 |
| Updated: | 1/11/2018 |
| Start Date: | July 2016 |
| End Date: | December 2017 |
The purpose of this study is to evaluate the association of Rheumatoid Arthritis (RA)-related
antibodies and periodontal inflammation in subjects at-risk for Rheumatoid Arthritis.
Subjects will undergo periodontal and joint examinations, as well as collection of body
fluids to measure Rheumatoid Arthritis-related antibodies.
antibodies and periodontal inflammation in subjects at-risk for Rheumatoid Arthritis.
Subjects will undergo periodontal and joint examinations, as well as collection of body
fluids to measure Rheumatoid Arthritis-related antibodies.
Inclusion Criteria:
- Rheumatoid Arthritis-antibody positivity (anti-CCP) in the absence of arthritis or
- Early RA <36 months since diagnosis
Exclusion Criteria:
- Pregnancy
- Antibiotic use prior to dental procedures or cleanings
- Wear dentures
- <18 years old
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