Efficacy of 1540 Nanometer Erbium Glass Laser to Improve Benign Dermatofibromas

The main objective of this study is to find a more effective treatment for itchy, painful or
unsightly dermatofibromas, that will improve symptoms of itch and/or pain and/or improve the
appearance of dermatofibromas. A secondary objective of this study is to better understand
the 1540 nanometer Erbium glass laser and its impact on the skin.

This is an open-label study where subjects will receive a laser treatment at week 0, and week
4, and then have 2 additional follow-up visits (no laser treatment at these visits).
Photographs will be taken at each visit and rated by blinded reviewers after the study to
determine efficacy.

Inclusion Criteria:

- female or male, age 18-65, have at least one dermatofibroma of the skin, on the trunk
or extremities, diagnosed by dermatologist, dermatofibroma is either itchy, painful or
unattractive to the patient.

Exclusion Criteria:

- previous treatment to the dermatofibroma(s), pregnant or nursing women, diabetic,
smoker, psoriasis, lupus or other autoimmune diseases, patient with a clear history of
keloids or poor wound healing. This study will exclude dermatofibroma lesions on the
face and genitals.