Molecular Testing to Direct Extent of Initial Thyroid Surgery
| Status: | Recruiting |
|---|---|
| Conditions: | Cancer, Cancer, Endocrine, Thyroid Cancer |
| Therapuetic Areas: | Endocrinology, Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/6/2019 |
| Start Date: | February 1, 2017 |
| End Date: | February 2020 |
| Contact: | Linwah Yip, MD |
| Email: | yipl@upmc.edu |
| Phone: | 412-647-0467 |
The research study consists of the participant agreeing to 1) the use of preoperative
molecular testing (ThyroSeq) to guide extent of initial surgery and 2) the prospective
collection of medical record data related to treatment of thyroid cancer.
molecular testing (ThyroSeq) to guide extent of initial surgery and 2) the prospective
collection of medical record data related to treatment of thyroid cancer.
The aim of the proposed pilot study is to use a clinical algorithm that incorporates
molecular, clinical and radiographic factors to inform surgical management. This study is the
first to propose molecular-directed surgical management for this commonly diagnosed cancer.
molecular, clinical and radiographic factors to inform surgical management. This study is the
first to propose molecular-directed surgical management for this commonly diagnosed cancer.
Inclusion Criteria:
- Thyroid nodule is >1.5 cm
- Preoperative FNA biopsy that is positive for papillary thyroid cancer or suspicious
for papillary thyroid cancer
Exclusion Criteria:
- Prior thyroid/parathyroid surgery
- Clinical indications for total thyroidectomy including hypothyroidism, history of head
or neck radiation when <18 years old
- Recurrent laryngeal nerve dysfunction
- Diagnosis of concurrent primary hyperparathyroidism
We found this trial at
1
site
4200 Fifth Ave
Pittsburgh, Pennsylvania 15260
Pittsburgh, Pennsylvania 15260
(412) 624-4141
Phone: 412-647-0467
University of Pittsburgh The University of Pittsburgh is a state-related research university, founded as the...
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