Trial of Unicompartmental Versus Total Knee Arthroplasty



Status:Recruiting
Conditions:Osteoarthritis (OA)
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - 75
Updated:7/8/2018
Start Date:May 22, 2018
End Date:January 2020
Contact:Nancy Parks, MS
Email:nparks@aori.org
Phone:703-619-4423

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Trial Summary
Trial Overview
Inclusion Criteria

A Prospective Randomized Trial of Unicompartmental Versus Total Knee Arthroplasty for the Treatment of Medial Compartment Osteoarthritis

This study is a prospective, randomized trial to compare patient outcomes of unicompartmental
knee arthroplasty (UKA) and total knee arthroplasty (TKA) for the treatment of medial
compartment osteoarthritis.


Inclusion Criteria:

- medial compartment osteoarthritis of the knee

- knee flexion greater than greater than 90 degrees

- flexion contracture of less than 10 degrees

- varus deformity < 20 degrees

- grade IV degeneration of the medial compartment

Exclusion Criteria:

- lateral compartment degenerative changes

- previous lateral meniscectomy

- anterior cruciate ligament deficiency

- body mass index > 40

- inflammatory arthritis

- history of septic arthritis

- hemoglobin A1c > 8.0

- chronic liver disease

- stage 3A or greater chronic renal disease

- active IV drug abuse

- patients requiring thromboembolic prophylaxis
We found this trial at
2
sites
Rush University Medical Center
1653 W. Congress Parkway
Chicago, Illinois 60612
(312) 942-5000
Principal Investigator: Craig Della Valle, MD
Phone: 312-432-2470
Rush University Medical Center Rush University Medical Center encompasses a 664-bed hospital serving adults and...
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Anderson Orthopaedic Research Institute
Alexandria, Virginia 22306
Principal Investigator: Kevin B Fricka, MD
Phone: 703-619-4423
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