Telmisartan (Micardis) and Ramipril (Altace) - Factorial Design Study for the Treatment of Hypertension



Status:Completed
Conditions:High Blood Pressure (Hypertension)
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:12/30/2017
Start Date:April 2006

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Randomized, Double-blind, Double-dummy, Placebo-controlled, 3x4 Factorial Design Trial to Evaluate Telmisartan 20 and 80 mg Tablets in Combination With Ramipril 1.25, 10, and 20 mg Capsules After Eight Weeks of Treatment in Patients With Stage I or II Hypertension, With an ABPM Sub-study

To identify dose combinations of telmisartan and ramipril that are more effective in reducing
diastolic blood pressure than each of the respective monotherapies in patients with Stage I
or II hypertension.


Inclusion Criteria:

- Male and female patients >=18 years of age with Stage I or II hypertension defined as:

- a mean seated cuff diastolic blood pressure >=95 and <=119 mmHg Main

Exclusion Criteria:

- Pregnant

- breast-feeding

- unwilling to use birth control during the study

- secondary hypertension

- SBP>=180 mmHg

- DBP>=120 mmHg

- severe renal dysfunction

- hepatic insufficiency

- stroke within the last 6 months

- myocardial infarction, cardiac surgery, percutaneous transluminal coronary
angioplasty, unstable angina or coronary artery bypass graft within the past three
months

- unstable or uncontrolled diabetes

- history of angioedema of either of the study drugs, and hypersensitivity to the study
drugs.
We found this trial at
62
sites
205.452.01038 Boehringer Ingelheim Investigational Site
Encinitas, California
82
mi
from 91732
Encinitas, CA
Click here to add this to my saved trials
Boehringer Ingelheim Investigational Site
Albuquerque, New Mexico
649
mi
from 91732
Albuquerque, NM
Click here to add this to my saved trials
205.452.01364 Boehringer Ingelheim Investigational Site
Auburn, Maine
2615
mi
from 91732
Auburn, ME
Click here to add this to my saved trials
1245.20.10128 Boehringer Ingelheim Investigational Site
Avon, Indiana
1780
mi
from 91732
Avon, IN
Click here to add this to my saved trials
1245.28.10033 Boehringer Ingelheim Investigational Site
Blue Ridge, Georgia
1910
mi
from 91732
Blue Ridge, GA
Click here to add this to my saved trials
1237.5.01015 Boehringer Ingelheim Investigational Site
Boulder, Colorado
812
mi
from 91732
Boulder, CO
Click here to add this to my saved trials
502.476.067 Boehringer Ingelheim Investigational Site
Buena Park, California
14
mi
from 91732
Buena Park, CA
Click here to add this to my saved trials
1200.75.54005 Boehringer Ingelheim Investigational Site
Buenos Aires,
6113
mi
from 91732
Buenos Aires,
Click here to add this to my saved trials
1236.1.555 Boehringer Ingelheim Investigational Site
Cadillac, Michigan 49601
1867
mi
from 91732
Cadillac, MI
Click here to add this to my saved trials
1218.74.01105 Boehringer Ingelheim Investigational Site
Carrollton, Texas
1216
mi
from 91732
Carrollton, TX
Click here to add this to my saved trials
Boehringer Ingelheim Investigational Site
Cincinnati, Ohio
1880
mi
from 91732
Cincinnati, OH
Click here to add this to my saved trials
Boehringer Ingelheim Investigational Site
Columbus, Ohio
1960
mi
from 91732
Columbus, OH
Click here to add this to my saved trials
1264.3.01031 Boehringer Ingelheim Investigational Site
Concord, California
350
mi
from 91732
Concord, CA
Click here to add this to my saved trials
205.452.01189 Boehringer Ingelheim Investigational Site
Corvallis, Oregon
776
mi
from 91732
Corvallis, OR
Click here to add this to my saved trials
1236.1.534 Boehringer Ingelheim Investigational Site
Cumberland, Rhode Island
2560
mi
from 91732
Cumberland, RI
Click here to add this to my saved trials
1268.17.01045 Boehringer Ingelheim Investigational Site
Deland, Florida
2177
mi
from 91732
Deland, FL
Click here to add this to my saved trials
205.452.01323 Boehringer Ingelheim Investigational Site
Erie, Pennsylvania
2117
mi
from 91732
Erie, PA
Click here to add this to my saved trials
205.452.01341 Boehringer Ingelheim Investigational Site
Eugene, Oregon
740
mi
from 91732
Eugene, OR
Click here to add this to my saved trials
1236.1.541 Boehringer Ingelheim Investigational Site
Excelsior Springs, Missouri 64024
1362
mi
from 91732
Excelsior Springs, MO
Click here to add this to my saved trials
1220.48.0043 Boehringer Ingelheim Investigational Site
Falls Church, Virginia
2273
mi
from 91732
Falls Church, VA
Click here to add this to my saved trials
1311.3.10103 Boehringer Ingelheim Investigational Site
Farmington, Connecticut
2491
mi
from 91732
Farmington, CT
Click here to add this to my saved trials
1301.1.5727 Boehringer Ingelheim Investigational Site
Glendale, Arizona
336
mi
from 91732
Glendale, AZ
Click here to add this to my saved trials
1236.1.505 Ledeeach Family Medicine
658 Harleysville Pike
Harleysville, Pennsylvania 19438
2361
mi
from 91732
Harleysville, PA
Click here to add this to my saved trials
205.452.01269 Boehringer Ingelheim Investigational Site
Haverhill, Massachusetts
2576
mi
from 91732
Haverhill, MA
Click here to add this to my saved trials
205.452.01209 Boehringer Ingelheim Investigational Site
Hialeah, Florida
2315
mi
from 91732
Hialeah, FL
Click here to add this to my saved trials
Boehringer Ingelheim Investigational Site
Houston, Texas
1357
mi
from 91732
Houston, TX
Click here to add this to my saved trials
1236.1.546 River Cities Cardiology Research Inst of Middle America
41 Quartermaster Court
Jeffersonville, Indiana 47130
1814
mi
from 91732
Jeffersonville, IN
Click here to add this to my saved trials
205.452.01184 Boehringer Ingelheim Investigational Site
Jupiter, Florida
2296
mi
from 91732
Jupiter, FL
Click here to add this to my saved trials
1245.25.10156 Boehringer Ingelheim Investigational Site
Kettering, Ohio
1898
mi
from 91732
Kettering, OH
Click here to add this to my saved trials
1160.128.1054 Boehringer Ingelheim Investigational Site
Largo, Florida
2118
mi
from 91732
Largo, FL
Click here to add this to my saved trials
1218.61.01052 Boehringer Ingelheim Investigational Site
Las Vegas, Nevada
217
mi
from 91732
Las Vegas, NV
Click here to add this to my saved trials
1199.14.1181 Boehringer Ingelheim Investigational Site
Long Beach, California
23
mi
from 91732
Long Beach, CA
Click here to add this to my saved trials
Boehringer Ingelheim Investigational Site
Los Angeles, California
13
mi
from 91732
Los Angeles, CA
Click here to add this to my saved trials
1199.14.1186 Boehringer Ingelheim Investigational Site
Madison, Wisconsin
1656
mi
from 91732
Madison, WI
Click here to add this to my saved trials
1245.28.10020 Boehringer Ingelheim Investigational Site
Medford, Oregon
627
mi
from 91732
Medford, OR
Click here to add this to my saved trials
502.476.106 Boehringer Ingelheim Investigational Site
Menomonee Falls, Wisconsin
1720
mi
from 91732
Menomonee Falls, WI
Click here to add this to my saved trials
1218.61.01040 Boehringer Ingelheim Investigational Site
Meridian, Idaho
664
mi
from 91732
Meridian, ID
Click here to add this to my saved trials
1236.1.503 Anchor Research Center
15205 Collier Boulevard
Naples, Florida 34119
2223
mi
from 91732
Naples, FL
Click here to add this to my saved trials
1199.14.1057 Boehringer Ingelheim Investigational Site
New Port Richey, Florida
2114
mi
from 91732
New Port Richey, FL
Click here to add this to my saved trials
1245.23.10157 Boehringer Ingelheim Investigational Site
Newton, Kansas
1183
mi
from 91732
Newton, KS
Click here to add this to my saved trials
1222.29.11004 Boehringer Ingelheim Investigational Site
North Dartmouth, Massachusetts
2585
mi
from 91732
North Dartmouth, MA
Click here to add this to my saved trials
1218.64.10018 Boehringer Ingelheim Investigational Site
Pembroke Pines, Florida
2310
mi
from 91732
Pembroke Pines, FL
Click here to add this to my saved trials
1200.43.00106 Boehringer Ingelheim Investigational Site
Peoria, Illinois
1618
mi
from 91732
Peoria, IL
Click here to add this to my saved trials
Boehringer Ingelheim Investigational Site
Portland, Oregon
827
mi
from 91732
Portland, OR
Click here to add this to my saved trials
1236.1.566 Boehringer Ingelheim Investigational Site
Richmond, Kentucky
1893
mi
from 91732
Richmond, KY
Click here to add this to my saved trials
1218.83.11014 Boehringer Ingelheim Investigational Site
Roseville, California
370
mi
from 91732
Roseville, CA
Click here to add this to my saved trials
205.452.01001 Boehringer Ingelheim Investigational Site
Salt Lake City, Utah
570
mi
from 91732
Salt Lake City, UT
Click here to add this to my saved trials
Boehringer Ingelheim Investigational Site
San Antonio, Texas
1188
mi
from 91732
San Antonio, TX
Click here to add this to my saved trials
502.476.097 Boehringer Ingelheim Investigational Site
Sandy, Utah
?
mi
from 91732
Sandy, UT
Click here to add this to my saved trials
Boehringer Ingelheim Investigational Site
Spartanburg, South Carolina
2043
mi
from 91732
Spartanburg, SC
Click here to add this to my saved trials
9.197.001 Boehringer Ingelheim Investigational Site
Tempe, Arizona
351
mi
from 91732
Tempe, AZ
Click here to add this to my saved trials
1236.1.570 Boehringer Ingelheim Investigational Site
The Colony, Texas
1215
mi
from 91732
The Colony, TX
Click here to add this to my saved trials
1245.25.10162 Boehringer Ingelheim Investigational Site
Tipton, Pennsylvania
2208
mi
from 91732
Tipton, PA
Click here to add this to my saved trials
1236.1.525 Physicians Research Center, LLC, Toms River
9 Mule Road
Toms River, New Jersey 08755
2424
mi
from 91732
Toms River, NJ
Click here to add this to my saved trials
205.452.01221 Boehringer Ingelheim Investigational Site
Troy, Michigan
1962
mi
from 91732
Troy, MI
Click here to add this to my saved trials
1268.17.01043 Boehringer Ingelheim Investigational Site
Tucson, Arizona
426
mi
from 91732
Tucson, AZ
Click here to add this to my saved trials
205.452.01307 Boehringer Ingelheim Investigational Site
Tulsa, Oklahoma
1250
mi
from 91732
Tulsa, OK
Click here to add this to my saved trials
205.452.01362 Boehringer Ingelheim Investigational Site
Tustin, California
25
mi
from 91732
Tustin, CA
Click here to add this to my saved trials
1245.25.10206 Boehringer Ingelheim Investigational Site
Valparaiso, Indiana
1755
mi
from 91732
Valparaiso, IN
Click here to add this to my saved trials
1236.1.561 Clinical Research Center of Cape Cod
131 Attucks Lane
West Yarmouth, Massachusetts 02601
2619
mi
from 91732
West Yarmouth, MA
Click here to add this to my saved trials
1218.74.01069 Boehringer Ingelheim Investigational Site
Westlake Village, California
46
mi
from 91732
Westlake Village, CA
Click here to add this to my saved trials
1199.14.1097 Boehringer Ingelheim Investigational Site
Wichita, Kansas
1181
mi
from 91732
Wichita, KS
Click here to add this to my saved trials