A Study of LY3002813 in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ)
| Status: | Recruiting |
|---|---|
| Conditions: | Alzheimer Disease |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 60 - 85 |
| Updated: | 4/5/2019 |
| Start Date: | December 18, 2017 |
| End Date: | September 16, 2021 |
| Contact: | There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or |
| Email: | ClinicalTrials.gov@lilly.com |
| Phone: | 1-317-615-4559 |
Assessment of Safety, Tolerability and Efficacy of LY3002813 in Early Symptomatic Alzheimer's Disease
The purpose of this study is to evaluate the safety, tolerability and efficacy of LY3002813
in early symptomatic Alzheimer's disease.
in early symptomatic Alzheimer's disease.
Inclusion Criteria:
- Gradual and progressive change in memory function reported by participants or
informants for ≥ 6 months.
- MMSE score of 20 to 28 (inclusive) at baseline or an acceptable historical
flortaucipir PET scan within 6 months prior to baseline that meets the central read
criteria.
- Meet 18F flortaucipir PET scan criteria.
- Meet 18F florbetapir PET scan (central read) criteria.
Exclusion Criteria:
- Have a history of long QT syndrome.
- Have received treatment with a stable dose of an acetylcholinesterase inhibitor
(AChEI) and/or memantine for less than 2 months before randomization.
- Contraindication to MRI.
We found this trial at
58
sites
593 Eddy Street
Providence, Rhode Island 02903
Providence, Rhode Island 02903
401-444-4000
Principal Investigator: Brian R. Ott
Phone: 401-444-6440
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
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3924 9th Avenue West
Bradenton, Florida 34205
Bradenton, Florida 34205
Principal Investigator: William McElveen
Phone: 941-708-0005
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4085 University Blvd S # 1
Jacksonville, Florida 32216
Jacksonville, Florida 32216
Principal Investigator: Carolyn M Tran
Phone: 904-730-0101
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100 West Gore St # 202
Orlando, Florida 32806
Orlando, Florida 32806
(407) 426-9299
Principal Investigator: Ira J Goodman
Phone: 407-426-9299
Compass Research LLC Compass Research is a clinical research company dedicated to testing new medications...
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Sarasota, Florida 34232
Principal Investigator: Mauricio Concha
Phone: 941-203-3750
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3212 Cove Bend Drive
Tampa, Florida 33613
Tampa, Florida 33613
Principal Investigator: Mary Stedman
Phone: 813-971-8311
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Atlantis, Florida 33462
Principal Investigator: Mark A Goldstein
Phone: 561-968-2933
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3570 Warrensville Center Road
Beachwood, Ohio 44122
Beachwood, Ohio 44122
Principal Investigator: Deborah Gould
Phone: 216-526-1843
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115 Mill St
Belmont, Massachusetts 02478
Belmont, Massachusetts 02478
(617) 855-2000
Principal Investigator: BRENT FORESTER
Phone: 617-855-3622
McLean Hospital McLean Hospital is a comprehensive psychiatric hospital committed to providing easy access to...
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Bennington, Vermont 05201
Principal Investigator: Cynthia Murphy
Phone: 802-447-1409
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Charlotte, North Carolina 28211
Principal Investigator: Oleg Tcheremissine
Phone: 704-446-7504
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Chicago, Illinois 60640
Principal Investigator: Jeffrey S. Ross
Phone: 773-275-3500
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Columbus, Ohio 43210
Principal Investigator: Douglas W. Scharre
Phone: 614-293-4969
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Dallas, Texas 75214
Principal Investigator: Charles F Greenfield
Phone: 2148273610258
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Danbury, Connecticut 06810
Principal Investigator: Samuel H Markind
Phone: 203-748-2551
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Dayton, Ohio 45414
Principal Investigator: Joel Vandersluis
Phone: 937-224-8200
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Delray Beach, Florida 33445
Principal Investigator: Mark L Brody
Phone: 561-374-8461
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Elk Grove Village, Illinois 60007
Principal Investigator: CONCETTA FORCHETTI
Phone: 847-593-8553
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100 Eisenhower Drive
Fairfax, Virginia 22031
Fairfax, Virginia 22031
Principal Investigator: James L Bicksel
Phone: 703-520-9703
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Fairway, Kansas 66205
Principal Investigator: Jeffrey M. Burns
Phone: 913-588-0555
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Fullerton, California 92835
Principal Investigator: Anthony M Ciabarra
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Greensboro, North Carolina 27405
Principal Investigator: Pramod Sethi
Phone: 336-273-2511
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Hollywood, Florida 33021
Principal Investigator: Harvey Schwartz
Phone: 954-366-0277
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Indianapolis, Indiana 46256
Principal Investigator: Kristi George
Phone: 317-537-6060
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340 W 10th St #6200
Indianapolis, Indiana 46202
Indianapolis, Indiana 46202
(317) 274-3772
Principal Investigator: Jared Brosch
Phone: 317-963-7402
Indiana University School of Medicine With more than 2,000 students in 2013, the Indiana University...
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Irvine, California 92618
Principal Investigator: Elly R Lee
Phone: 9497531663x226
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Irvine, California 92697
Principal Investigator: Joshua Grill
Phone: 949-824-3250
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Las Vegas, Nevada 89113
Principal Investigator: Bharat R Mocherla
Phone: 702-750-0222 EXT 102
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Merritt Island, Florida 32952
Principal Investigator: Gregory Kirk
Phone: 321-305-5015
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Methuen, Massachusetts 01844
Principal Investigator: Michael J McCartney
Phone: 978-655-7155
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Miami, Florida 33126
Principal Investigator: Jorge M Venereo
Phone: 305-262-4321
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Miami, Florida 33137
Principal Investigator: Marc Agronin
Phone: 305-514-8535
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New Port Richey, Florida 34652
Principal Investigator: Vikram Atit
Phone: 727-849-4131
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Newport Beach, California 92660
Principal Investigator: Nader Oskooilar
Phone: 949-752-7936
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Newton, Massachusetts 02459
Principal Investigator: Paul R. Solomon
Phone: 617-699-6927
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8895 North Military Trail
Palm Beach Gardens, Florida 33410
Palm Beach Gardens, Florida 33410
Principal Investigator: Michael Tuchman
Phone: 561-694-1010
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Phoenix, Arizona 85006
Principal Investigator: David Anthony Weidman
Phone: 602-839-6631
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Plymouth, Massachusetts 02360
Principal Investigator: Donald Marks
Phone: 508-746-5060
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Pompano Beach, Florida 33064
Principal Investigator: Jose E De La Gandara
Phone: 954-786-7331
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Port Orange, Florida 32127
Principal Investigator: Alexander J White
Phone: 386-304-7070
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345 Blackstone Blvd
Providence, Rhode Island 02906
Providence, Rhode Island 02906
(401) 455-6200
Principal Investigator: Stephen P Salloway
Phone: 401-455-6403
Butler Hospital Founded in 1844, Butler Hospital is the state's only non-profit, free-standing psychiatric hospital...
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Raleigh, North Carolina 27607
Principal Investigator: Bradley J Robottom
Phone: 919-782-3456
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Richmond, Virginia 23294
Principal Investigator: John K Scott
Phone: 804-672-2995
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Saint Louis, Missouri 63110
Principal Investigator: BARBARA SNIDER
Phone: 314-286-2523
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San Diego, California 92103
Principal Investigator: Stephen Thein
Phone: 619-294-4302
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San Diego, California 92123
Principal Investigator: MICHAEL PLOPPER
Phone: 858-836-8355
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Santa Ana, California 92705
Principal Investigator: John Duffy
Phone: 7145423008301
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Stamford, Connecticut 06905
Principal Investigator: Peter J McAllister
Phone: 203-914-1903
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Sun City, Arizona 85351
Principal Investigator: Edward Zamrini
Phone: 623-832-6530
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The Villages, Florida 32162
Principal Investigator: Jay J Rubin
Phone: 352-261-0901
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Toms River, New Jersey 08755
Principal Investigator: Sanjiv K Sharma
Phone: 732-341-9500
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Topeka, Kansas 66606
Principal Investigator: Katherine J Willingham
Phone: 785-354-9591
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Willow Grove, Pennsylvania 19090
Principal Investigator: David C Weisman
Phone: 215-957-9250
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Winston-Salem, North Carolina 27103
Principal Investigator: Franklin Giles Crowell
Phone: 336-794-8165
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