Abuse Liability of Reduced Nicotine Content Cigarettes Within a Complex Tobacco Marketplace



Status:Recruiting
Conditions:Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 65
Updated:2/27/2019
Start Date:January 2017
End Date:July 2020
Contact:Brent Kaplan, PhD
Email:bkaplan4@vtc.vt.edu

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Tobacco regulatory policies can have unanticipated consequences; therefore, methods that
would permit prospective estimates of the effects of potential tobacco regulations are
necessary for the development of tobacco regulatory science. The goal of this project is to
experimentally assess how smokers purchase and consume reduced-nicotine cigarettes. In
experiment 1, we will investigate how purchasing/consuming reduced-nicotine cigarettes is
related to nicotine content and absorption. In experiment 2, we will investigate how
purchasing/consuming changes when other nicotine products are available in an experimental
marketplace setting. The proposed projects can directly inform tobacco regulation by
providing estimates of the real-world effects of novel policies.


Inclusion Criteria:

- smoke at least 5 cigarettes per day

- have a breath carbon monoxide (CO) level of at least 10 ppm at intake

- no immediate plans to quit smoking.

Exclusion Criteria:

- pregnant, lactating, plans to become pregnant

- weigh more than 110lbs (experiment 1 only)

- have plans to move out of the area during the course of the experiment

To see if you are eligible, use the following confidential link:
http://vtcri.info/arrcclinicaltrials
We found this trial at
1
site
Roanoke, Virginia 24016
Principal Investigator: Mikhail N Koffarnus, PhD
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mi
from
Roanoke, VA
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