Oncology Research Information Exchange Network in Improving Genetic Screening Rate in Patients With Cancer

PRIMARY OBJECTIVES:

I. Measure the change in uptake of cancer genetic referrals and genetic testing in the ORIEN
system of cancer centers implementing the Progeny Family History Questionnaire (FHQ).

SECONDARY OBJECTIVES:

I. Follow and estimate utilization of preventive health behaviors among Progeny FHQ users
across all institutions.

II. Compare utilization of preventive health behavior between Progeny FHQ risk identification
and genetic testing.

OUTLINE:

Patients take Progeny Genetic Pedigree and Family History Questionnaire. Results are reviewed
by the site specific research coordinator and/or genetic counselor to assess whether a
patient fulfills criteria for referral to the site specific cancer genetics clinic for
further evaluation.

After completion of study, patients are followed up at 6 months after disclosure of genetic
testing results.

Inclusion Criteria:

- Limited to those patients who are consented to the Total Cancer Care Protocol (TCCP)
protocol

- Able to understand and sign the TCCP informed consent, California subject?s bill of
rights, Health Insurance Portability and Accountability Act (HIPAA), and research
authorization form directly or through an authorized representative; the informed
consent, subject?s bill of rights, HIPAA, and research authorization will be available
in both English and Spanish languages

Exclusion Criteria:

- Individuals who are not registered as patients for outpatient or inpatient care to the
TCCP protocol

- Individuals who are unable to understand or sign the TCCP informed consent, subject?s
bill of rights, HIPAA, and research authorization in either English or Spanish