A Pilot Study to Assess Theragnostically Planned Liver Radiation With Functional DVH Analysis to Optimize Individualized Radiation Therapy
| Status: | Recruiting |
|---|---|
| Conditions: | Liver Cancer, Liver Cancer, Liver Cancer, Cancer, Cancer, Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 12/14/2018 |
| Start Date: | June 13, 2017 |
| End Date: | December 1, 2020 |
| Contact: | Jill Deluca |
| Email: | jdelucca@iupui.edu |
| Phone: | 317-944-2524 |
The purpose of this study is to compare radiation treatment plans that are designed for
patients with liver cancer. One treatment plan will be created using routine procedures and
scans normally performed for radiation treatment planning. The other treatment plan will be
created using routine procedures with the addition of two imaging scans; a HIDA
(Hepatobiliary Iminodiacetic Acid) scan and an MRI (Magnetic Resonance Imaging) scan. This
study will evaluate if adding these imaging scans to treatment planning can reduce the amount
of radiation to healthy liver tissue during treatment.
patients with liver cancer. One treatment plan will be created using routine procedures and
scans normally performed for radiation treatment planning. The other treatment plan will be
created using routine procedures with the addition of two imaging scans; a HIDA
(Hepatobiliary Iminodiacetic Acid) scan and an MRI (Magnetic Resonance Imaging) scan. This
study will evaluate if adding these imaging scans to treatment planning can reduce the amount
of radiation to healthy liver tissue during treatment.
Inclusion Criteria:
- Primary liver malignancy including hepatocellular carcinoma (HCC) or
cholangiocarcinoma
- Subjects must have a Child-Turcotte-Pugh (CTP) score ≤ 7 to be eligible
Exclusion Criteria:
- Subjects who are pregnant or planning to become pregnant during the study.
- No more than 3 lesions can be treated. Total diameter of all lesions must be less than
or equal to 6 cm
- Prior radiation treatment to the upper abdomen
- Active infection, active upper GI ulceration or hemorrhage, symptomatic congestive
heart failure, unstable angina pectoris, cardiac arrhythmia
We found this trial at
1
site
535 Barnhill Dr
Indianapolis, Indiana 46202
Indianapolis, Indiana 46202
(888) 600-4822
Phone: 317-944-2524
Indiana University Melvin and Bren Simon Cancer Center At the IU Simon Cancer Center, more...
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