A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer



Status:Recruiting
Conditions:Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:12/22/2018
Start Date:December 15, 2017
End Date:December 15, 2020
Contact:Recruiting sites have contact information. Please contact the sites directly. If there is no contact information
Email:Clinical.Trials@bms.com
Phone:please email:

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A Phase 2 Study of Cabiralizumab (BMS-986227, FPA008) Administered in Combination With Nivolumab (BMS-936558) With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer

The purpose of this study is to determine whether an investigational immuno-therapy,
cabiralizumab in combination with nivolumab, with or without chemotherapy, is effective for
the treatment of advanced pancreatic cancer.


Inclusion Criteria:

- Must have histological or cytological confirmed diagnosis of locally advanced or
metastatic adenocarcinoma of the pancreas, which has progressed on or after one line
of chemotherapy

- ECOG Performance status 0-1

- Adequate organ functions

- Measurable disease

Exclusion Criteria:

- Suspected or known CNS metastasis

- Participants with active, known, or suspected autoimmune disease

- Uncontrolled or significant cardiovascular disease

- Prior exposure to selected immune cell-modulating antibody regimens
We found this trial at
21
sites
Aurora, Colorado 80045
Phone: 720-848-0983
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3400 N Charles St
Baltimore, Maryland 21205
410-516-8000
Phone: 410-614-2748
Johns Hopkins University The Johns Hopkins University opened in 1876, with the inauguration of its...
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Baltimore, MD
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330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Phone: 617-975-7409
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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Boston, MA
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185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
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Boston, MA
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Baltimore, Maryland 21231
Phone: 410-614-3644
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Baltimore, MD
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450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Boston, MA
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2201 Inwood Rd
Dallas, Texas 75235
(214) 645-8300
Phone: 214-648-7031
U.T. Southwestern Medical Center The story of UT Southwestern Medical Center is one of commitment...
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Dallas, TX
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Dallas, Texas 75246
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Edmonton, Alberta
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Edmonton,
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Houston, Texas 77030
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Houston, TX
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757 Westwood Plaza
Los Angeles, California 90024
(310) 825-9111
Phone: 310-582-4069
UCLA Medical Center Founded in 1955, UCLA Medical Center became Ronald Reagan UCLA Medical Center...
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Los Angeles, CA
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250 25th Ave N, Ste 100
Nashville, Tennessee 37023
615-320-5090
Phone: 615-329-7628
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
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Nashville, TN
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1275 York Ave
New York, New York 10021
(212) 639-2000
Phone: 646-888-4182
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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New York, NY
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3451 Walnut St
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Phone: 215-955-8293
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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Philadelphia, PA
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Phoenix, Arizona 85054
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Pittsburgh, Pennsylvania 15213
Phone: 412-864-7820
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Saint Louis, Missouri 63110
Phone: 314-747-6268
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Scottsdale, Arizona 85258
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Scottsdale, Arizona 85258
Phone: 623-238-7671
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Seattle, Washington 98109
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Seattle, WA
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