VCRC Tissue Repository



Status:Recruiting
Conditions:Cardiology, Cardiology, Cardiology, Cardiology, Cardiology, Hematology
Therapuetic Areas:Cardiology / Vascular Diseases, Hematology
Healthy:No
Age Range:Any
Updated:3/27/2019
Start Date:November 2016
End Date:December 2019
Contact:Sherry Xu
Email:sherryxu@pennmedicine.upenn.edu

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VCRC Tissue Biorepository Collection Protocol

The purpose of this study is to collect existing tissue specimens from subjects enrolled in
Vasculitis Clinical Research Consortium (VCRC) studies. Analysis of these tissue specimens
and linked clinical data collected through VCRC studies may lead to the identification and
development of a series of translational research projects. Results of these studies will
provide vasculitis researchers with insight into the causes of these diseases and generate
new ideas for diagnostic tests and therapies, and will be of great interest to the larger
communities of researchers investigating vasculitis and other autoimmune, inflammatory, and
vascular diseases.

Biopsy specimens collected as standard of care for these diseases will be retrieved and used
in research. The most common biopsies performed are kidney, lung, skin, nerves, and vessels;
however, other tissue is also of interest for the study. Biopsies are not performed as part
of this protocol, rather we will request consent to collect biopsy specimens already
collected under routine care.

Inclusion Criteria:

- A participant will be deemed eligible for this study if the participant is/was
enrolled in another one of the VCRC observational/longitudinal protocols (5502, 5503,
5504, 5505, 5506, 5507, 5563) and/or one of the VCRC interventional studies (5522,
5523, 5526, 5527, or 5562).

Exclusion Criteria:

- Inability to give informed consent (or their guardians in the case of children) and to
sign the consent form.

- Unwilling to allow the use of their tissue for research.
We found this trial at
7
sites
Hamilton, Ontario
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72 East Concord Street
Boston, Massachusetts 02118
(617) 638-5300
Boston University School of Medicine A leader in medical education and research, Boston University School...
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Boston, MA
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75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
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Boston, MA
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9500 Euclid Avenue
Cleveland, Ohio 44106
216.444.2200
Cleveland Clinic Cleveland Clinic is committed to principles as presented in the United Nations Global...
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Cleveland, OH
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4200 Fifth Ave
Pittsburgh, Pennsylvania 15260
(412) 624-4141
University of Pittsburgh The University of Pittsburgh is a state-related research university, founded as the...
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Pittsburgh, PA
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201 Presidents Circle
Salt Lake City, Utah 84108
801) 581-7200
University of Utah Research is a major component in the life of the U benefiting...
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Salt Lake City, UT
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3451 Walnut St
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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Philadelphia, PA
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